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The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29

Journal of Allergy and Clinical Immunology, 2008
Cytokines are involved in virtually every aspect of immunity and inflammation. A cascade of responses evolves after cytokine activation, although optimal function might ultimately involve several complementary cytokines. Understanding the function of individual cytokines is complicated because their role can vary depending on the cellular source ...
Scott, Commins, John W, Steinke, Larry, Borish   +2 more
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IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26

Immunology Letters, 2003
It has been reported that the CD4+ T cell is a very important source of interleukin 10 (IL-10), while CD8+ cells produce low amounts. IL-10 exerts several immune stimulating, as well as inhibitory effects. There are at least five novel human IL-10 family-related molecules: IL-19, IL-20, IL-22, IL-24, and IL-26.
P, Conti, D, Kempuraj, S, Frydas, K, Kandere, W, Boucher, R, Letourneau, B, Madhappan, K, Sagimoto, S, Christodoulou, T C, Theoharides   +9 more
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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.

Immunity, 2005
Cytokines of the interleukin-1 (IL-1) family, such as IL-1 alpha/beta and IL-18, have important functions in host defense, immune regulation, and inflammation. Insight into their biological functions has led to novel therapeutic approaches to treat human
J. Schmitz, Alexander M. Owyang, E. Oldham, Yaoli Song, E. Murphy, T. Mcclanahan, G. Zurawski, M. Moshrefi, J. Qin, Xiaoxia Li, D. Gorman, J. Fernando Bazan, R. Kastelein, Schering-Plough Biopharma   +13 more
semanticscholar   +1 more source