Results 201 to 210 of about 52,674 (356)

Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity

Advanced Science, EarlyView.
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li, Dapeng Sun, Wei Hao, Hua Fu, Yueli Zhang, Zhijian Li, Bo Qin, Yumei Wang, Sheng Cui   +8 more
wiley   +1 more source

Synthesis of Fused sp³-Enriched Imidazoles. [PDF]

ChemistryOpen
Lysenko V, Portiankin A, Shvydenko T, Shishkina S, Nazarenko K, Kostyuk A.   +5 more
europepmc   +1 more source

BIOLOGICAL ACTIVITY OF DIAZONIUM COMPOUNDS (II): POSITIVE INO- AND CHRONOTROPIC ACTIONS ON GUINEA PIG ATRIA OF 4 (OR 5)-DIAZO-IMIDAZOLE-5 (OR 4)-CARBOXAMIDE

, 1968
HEITAROH IWATAJ, Itaru Yamamoto, Makoto Oka   +2 more
openalex   +1 more source

Imidazole Catalyses in Aqueous Systems. III. Formation of the Catalyst-Substrate Complex in the Hydrolysis of a Phenyl Ester Catalyzed by a Naphthylimidazole Derivative [PDF]

, 1970
Toyoki Kunitake, Seiji Shinkai, Chuji Aso   +2 more
openalex   +1 more source

Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds

Advanced Science, EarlyView.
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She, Vera Engelbrecht, Jacek Kozuch, Ulf‐Peter Apfel, Sven T. Stripp, Anja Hemschemeier, Thomas Happe   +6 more
wiley   +1 more source

Mechanochemistry to Form Substituted Imidazoles, Imidazolium Salts and NHC-Gold Complexes with Fluorine-Containing Groups. [PDF]

Molecules
Salis C, Mohammedi S, Turazza L, Blandin Y, Garnier M, Hemmert C, Baltas M, Gornitzka H.   +7 more
europepmc   +1 more source

Reactivity of Peptide Imidazole, Amino, and Phenolic Groups towards p-Nitrophenyl Acetate

, 1963
Walter L. Koltun, Lionel Ng, Frank R.N. Gurd   +2 more
openalex   +1 more source

The Reaction of 3-Methyl-5-methylmercapto-2,4-diphenylthiazolium Iodide with Bases. Preparation of Mesoionic Imidazoles [PDF]

, 1970
Toshie Shiba, Hiroshi Kato
openalex   +1 more source

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Cooperative photoredox and N-heterocyclic carbene-catalyzed formal C-H acylation of cyclopropanes via a deconstruction-reconstruction strategy. [PDF]

Chem Sci
Gao F, Wang T, Yan X.
europepmc   +1 more source