Results 221 to 230 of about 95,350 (343)

Optically active imidazole N-oxides derived from l-prolinamine1

, 2013
Grzegorz Mlostoń, Aneta Wróblewska, Emilia Obijalska, Heinz Heimgartner   +3 more
openalex   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

An Efficient H‑Reduction Protocol for the Synthesis of Novel (Benz)imidazole-allyl Alcohol and Imidazole-1,3-diol Derivatives. [PDF]

ACS Omega
Mhasni O, Châabani N, Triaa N, Bouajila J, Rezgui F.   +4 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Serine encodes drug selectivity in human OAT1. [PDF]

Structure
Dai Y, Lee CH.
europepmc   +1 more source

Optoelectronic Properties Studies of Deep-Blue Emitters Base on Imidazole Derivative by Regulating Molecule Conjugation

Rong Zhang, Yue Li, Zhendong Lv, Tong Wang, Jun Zhao, Qing Li, Huaixin Wei   +6 more
openalex   +1 more source

Nonsteric factors dominate binding of nitric oxide, azide, imidazole, cyanide, and fluoride to the Rhizobial heme-based oxygen sensor FixL

, 1996
Wade C. Winkler, G. González, Jonathan B. Wittenberg, Russ Hille, Naveen Dakappagari, Anand Jacob, Leyla A. Gonzalez, Marie‐Alda Gilles‐Gonzalez   +7 more
openalex   +1 more source

Thermal Cyclotrimerization Bridges Polymer‐Filler Interfaces for High‐Performance CO2 Separation Membranes

Advanced Science, EarlyView.
Thermal cyclotrimerization of nitriles converts interfacial discontinuity in MAF‐stu‐1/PIM‐1 MMMs into a continuity‐enhanced junction. Triazine–Zn2+ coordination between TR‐PIM chains and MAF‐stu‐1, together with hydrogen bonding and π–π stacking, lowers interfacial tension and builds selective CO2 pathways, enabling > 10 000 barrer CO2 permeability ...
Zhihong Lin, Kaifang Wang, Ziyi Yuan, Jiali Tang, Xiaozhen Liu, Liu Chen, Lu Shao, Xuezhong He   +7 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on the Clinical Efficacy of Azole Antifungals. [PDF]

Genes (Basel)
Singam H, Mossad S.
europepmc   +1 more source