Results 51 to 60 of about 92,456 (380)
Oriental Journal of Chemistry, 2018 A simple, efficient procedure has been developed using N-cationic surfactant namely Benzethonium chloride (BzthCl, 10 mol%) as novel catalyst for the synthesis of 2,4,5-trisubstituted imidazoles by condensation of aldehyde, ammonium acetate and benzil ...
D. Parthiban, R. Karunakaran
semanticscholar +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Bulletin of the Chemical Society of Ethiopia, 2017 A simple and efficient method for one-pot synthesis of lophine derivatives (2,4,5-trisubstituted imidazoles) by using the benzyltriphenylphosphonium chloride (BTPPC), as a catalyst, under solvent-free conditions is described.
M. Alikarami, M. Amozad
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
Molbank, 2023 (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane.
Ryan B. Gaynor +2 more
doaj +1 more source
Glycerol confined in zeolitic imidazolate frameworks: The temperature-dependent cooperativity length scale of glassy freezing [PDF]
J. Chem. Phys. 150 (2019) 024504, 2018 In the present work, we employ broadband dielectric spectroscopy to study the molecular dynamics of the prototypical glass former glycerol confined in two microporous zeolitic imidazolate frameworks (ZIF-8 and ZIF-11) with well-defined pore diameters of 1.16 and 1.46 nm, respectively.
arxiv +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Groups of antifungal drugs with role in animal health - Synthesis [PDF]
Medicamentul Veterinar, 2021 Fungal infections are an important part of infectious pathology, their incidence increasing considerably, as a result of the widespread use of antibiotics, corticosteroids, cytostatics and immunosuppressive drugs.
Răzvan F. Moruzi +6 more
doaj
Molecules, 2023 A controllable synthesis of trisubstituted imidazoles and pyrroles has been developed through rhodium(II)-catalyzed regioselective annulation of N-sulfonyl-1,2,3-trizaoles with β-enaminones.
Hua Wang +4 more
doaj +1 more source
New protocols to access imidazoles and their ring fused analogues: synthesis from N-propargylamines
, 2017 Imidazole and its derivatives are privileged N-heterocyclic structures present in various natural products and synthetic pharmaceuticals. Despite the numerous methods that have been developed for the synthesis of imidazole cores, it is still challenging ...
E. Vessally +4 more
semanticscholar +1 more source