Results 61 to 70 of about 52,674 (356)

β–Cyclodextrin–Propyl Sulfonic Acid Catalysed One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles as Local Anesthetic Agents

open access: yesMolecules, 2015
Some functionalized 1,2,4,5-tetrasubstituted imidazole derivatives were synthesized using a one-pot, four component reaction involving 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines.
Yan Ran, Ming Li, Zong-Ze Zhang
doaj   +1 more source

Glyoxal uptake on ammonium sulphate seed aerosol: reaction products and reversibility of uptake under dark and irradiated conditions [PDF]

open access: yes, 2009
Chamber studies of glyoxal uptake onto ammonium sulphate aerosol were performed under dark and irradiated conditions to gain further insight into processes controlling glyoxal uptake onto ambient aerosol. Organic fragments from glyoxal dimers and trimers
Chan, A. W. H.   +6 more
core  

Conversion of imidazoles to imidazolones with chloramine-​B: kinetic and mechanistic study [PDF]

open access: yes, 2016
Oxidative conversion of 1H-​imidazole (IzlH) and 2-​substituted imidazoles viz., 2-​ethyl-​1H-​imidazole (2-​EtIzlH)​, 2-​methyl-​1H-​imidazole (2-​MeIzlH)​, 1H-​imidazole-​2-​ester (2-​EsIzlH)​, and 1H-​imidazole-​2-​carbaldehyde (2-​CaIzlH) to the ...
Manjunatha, A.S., Puttaswamy, .
core   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

Trisubstituted-imidazoles induce apoptosis in human breast cancer cells by targeting the oncogenic PI3K/Akt/mTOR signaling pathway [PDF]

open access: yes, 2016
Overactivation of PI3K/Akt/mTOR is linked with carcinogenesis and serves a potential molecular therapeutic target in treatment of various cancers. Herein, we report the synthesis of trisubstituted-imidazoles and identified 2-chloro-3-(4, 5-diphenyl-1H ...
Andreas, Bender.   +15 more
core   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Activity of the Ethanolic Extract Obtained from Citrus microcarpa Pericarps against Meloidogyne enterolobii, and Chemical Composition Analysis

open access: yesHortScience
Citrus microcarpa is a popular nutritious fruit that is widely cultivated in China. In recent years, many compounds with significant pharmacological activities have been isolated successfully from the pericarp of C. microcarpa.
Xiaoli Dou   +6 more
doaj   +1 more source

Versatile Microwave-Assisted and Lanthanum Chloride Catalysed Synthesis of Polysubstituted Imidazoles Using Urea/Thiourea as Benign Source of Ammonia

open access: yesE-Journal of Chemistry, 2012
Lanthanum chloride was found to be an effective catalyst for the facile and one-pot synthesis of polysubstituted imidazoles under solvent free condition in excellent yields.
Mohammad Reza Manafi   +2 more
doaj   +1 more source

Inhibition of microbial biofuel production in drought-stressed switchgrass hydrolysate [PDF]

open access: yes, 2016
Additional file 2. Maps of significant gene ontology terms for chemical genomics data. Untreated biomass composition.
Alan Higbee   +17 more
core   +4 more sources

Studien über Imidazole [PDF]

open access: yesJustus Liebigs Annalen der Chemie, 1893
n ...
openaire   +2 more sources

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