Results 31 to 40 of about 1,302 (169)
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Correction: Iminosugars as glycosyltransferase inhibitors
Organic & Biomolecular Chemistry, 2021 Correction for ‘Iminosugars as glycosyltransferase inhibitors’ by Irene Conforti, et al. , Org. Biomol. Chem. , 2021, DOI: 10.1039/D1OB00382H.
Irene Conforti, Alberto Marra
openaire +2 more sources
Natural Products and BioprospectingIminosugars, a class of polyhydroxylated cyclic alkaloids with intriguing properties, hold promising therapeutic potentials against a broad spectrum of enveloped viruses, including DENV, HCV, HIV, and influenza viruses.
Qiantong Liu +6 more
doaj +1 more source
A Bis-Glycosylamine Strategy for the Synthesis of Dimeric Iminosugars Based on a DAB-1 Scaffold
MoleculesA straightforward synthetic route towards DAB-1 scaffolded dimeric iminosugars is described here, starting from readily available bis-glycosylamines.
Kamilia Ould Lamara +5 more
doaj +1 more source
New Frontiers on Human Safe Insecticides and Fungicides: An Opinion on Trehalase Inhibitors
Molecules, 2020 In the era of green economy, trehalase inhibitors represent a valuable chance to develop non-toxic pesticides, being hydrophilic compounds that do not persist in the environment. The lesson on this topic that we learned from the past can be of great help
Camilla Matassini +2 more
doaj +1 more source
N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines
Chemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga +6 more
wiley +1 more source
Iminosugars and methods of treating Filoviral diseases [PDF]
, 2016 The present application relates to iminosugars and methods of treating viral infections with iminosugars and, in particular, to the use of iminosugars for treatment and/or prevention of viral infections caused by or associated with a virus belonging to ...
core
Glycomimetics at the Mirror: Medicinal Chemistry of L-Iminosugars
, 2009 Inhibition of carbohydrate processing enzymes is a topic of great interest, as these enzymes are involved in a plethora of key biochemical events, such as digestion, lysosomal catabolism of glycoconjugates and post-translational glycoprotein processing ...
GUARAGNA, ANNALISA +2 more
core +1 more source
Heteroatom modified carbohydrate scaffolds in drug discovery
Discover ChemistryCarbohydrate-derived heteroatom scaffolds have emerged as versatile frameworks in modern drug discovery due to their inherent stereochemical diversity, biocompatibility, and ability to engage biological targets through multiple noncovalent interactions ...
Jyoti Dahiya +2 more
doaj +1 more source
One-Pot Synthesis of Hydroxylated Alkaloids from Sugars via a Pictet–Spengler-Type Reaction
MoleculesAn efficient and convenient strategy has been successfully developed for the preparation of novel hydroxylated alkaloid derivatives (also called fused multicyclic iminosugars) from p-toluenesulfonylated sugars through a Pictet–Spengler-type mechanism ...
Likai Zhou +7 more
doaj +1 more source