Results 61 to 70 of about 73,161 (247)
Frontiers in Immunology, 2013 Imaging technology has undergone rapid growth with the development of super resolution microscopy, which enables resolution below the diffraction barrier of light (~200 nm).
Emily M. Mace +3 more
doaj +1 more source
Intraflagellar transport: a new player at the immune synapse [PDF]
Trends in Immunology, 2011 The assembly and maintenance of primary cilia, which orchestrate signaling pathways centrally implicated in cell proliferation, differentiation and migration, are ensured by multimeric protein particles in a process known as intraflagellar transport (IFT).
Finetti, Francesca +3 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Investigative and clinical applications of synthetic immune synapses [PDF]
WIREs Nanomedicine and Nanobiotechnology, 2012 AbstractThe immune synapse (IS) has emerged as a compelling model of cell–cell communication. This interface between a T cell and antigen‐presenting cell (APC) serves as a key point in coordinating the immune response. A distinguishing feature of this interface is that juxtacrine signaling molecules form complex patterns that are defined at micrometer ...
Michael C, Milone, Lance C, Kam
openaire +2 more sources
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse
eLife, 2016 T cell receptor (TCR) engagement opens Ca2+ release-activated Ca2+ (CRAC) channels and triggers formation of an immune synapse between T cells and antigen-presenting cells.
Catherine A Hartzell +3 more
doaj +1 more source
Visualizing the Immune Synapse
Biology of Blood and Marrow Transplantation, 2007 T cells that interact with antigen-specific APCs an mount a wide spectrum of responses that range rom induction of cytokine production and proliferaion to induction of anergy, as defined by lack of roliferation and IL-2 secretion [1-3], and even to riggering programmed cell death [4-8].
openaire +1 more source
Advanced Materials, EarlyView.This study presents a compact dynamic‐field‐driven nucleation and growth (DFNG) model that captures ferroelectric switching behavior under arbitrary voltage waveforms. It enables extraction of time‐dependent domain wall velocity and growth dimensionality, which can then be extended to device‐level modeling.
Yi Liang +10 more
wiley +1 more source
Dendritic Cells and HIV-1 Trans-Infection
Viruses, 2010 Dendritic cells initiate and sustain immune responses by migrating to sites of pathogenic insult, transporting antigens to lymphoid tissues and signaling immune specific activation of T cells through the formation of the immunological synapse.
David McDonald
doaj +1 more source
Advanced Materials Technologies, EarlyView.Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu +8 more
wiley +1 more source