Results 81 to 90 of about 1,158,960 (278)

An adaptive silicon synapse [PDF]

, 2003
Chicca E, Indiveri G, Douglas R. An adaptive silicon synapse. Presented at the Proceedings of the 2003 International Symposium on Circuits and Systems (ISCAS).We present an analog circuit for implementing models of synapses with short-term adaptation ...
Douglas, R., Indiveri, G., Chicca, Elisabetta ; https://orcid.org/   +2 more
core   +1 more source

Visualizing the Immune Synapse

Biology of Blood and Marrow Transplantation, 2007
T cells that interact with antigen-specific APCs an mount a wide spectrum of responses that range rom induction of cytokine production and proliferaion to induction of anergy, as defined by lack of roliferation and IL-2 secretion [1-3], and even to riggering programmed cell death [4-8].
openaire   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse

eLife, 2016
T cell receptor (TCR) engagement opens Ca2+ release-activated Ca2+ (CRAC) channels and triggers formation of an immune synapse between T cells and antigen-presenting cells.
Catherine A Hartzell, Katarzyna I Jankowska, Janis K Burkhardt, Richard S Lewis   +3 more
doaj   +1 more source

Etude de l'immuno-infiltration et du rôle fonctionnel des lymphocytes T cytotoxiques dans les lymphomes folliculaires [PDF]

, 2012
Le lymphome folliculaire (LF) est le second des lymphomes malins en fréquence. Le LF est une maladie encore considérée comme incurable. Dans ce contexte, l'immuno-intervention est une approche prometteuse dans la mesure où des données cliniques et ...
Laurent, Camille
core  

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Dendritic Cells and HIV-1 Trans-Infection

Viruses, 2010
Dendritic cells initiate and sustain immune responses by migrating to sites of pathogenic insult, transporting antigens to lymphoid tissues and signaling immune specific activation of T cells through the formation of the immunological synapse.
David McDonald
doaj   +1 more source

Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes

Journal of Extracellular Vesicles, 2020
T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule-organizing centre (MTOC) and the polarization of the MTOC to the immune synapse (IS). These events lead to exosome secretion at the IS.
Ana Bello-Gamboa, Marta Velasco, Solange Moreno, Gonzalo Herranz, Roxana Ilie, Silvia Huetos, Sergio Dávila, Alicia Sánchez, Jorge Bernardino De La Serna, Víctor Calvo, Manuel Izquierdo   +10 more
doaj   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source