Results 91 to 100 of about 76,481 (272)
Image_3_Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells.TIF [PDF]
, 2019 Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated.
Felipe Del Valle Batalla (6373913) +4 more
core +1 more source
Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse
eLife, 2016 T cell receptor (TCR) engagement opens Ca2+ release-activated Ca2+ (CRAC) channels and triggers formation of an immune synapse between T cells and antigen-presenting cells.
Catherine A Hartzell +3 more
doaj +1 more source
Visualizing the Immune Synapse
Biology of Blood and Marrow Transplantation, 2007 T cells that interact with antigen-specific APCs an mount a wide spectrum of responses that range rom induction of cytokine production and proliferaion to induction of anergy, as defined by lack of roliferation and IL-2 secretion [1-3], and even to riggering programmed cell death [4-8].
openaire +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Video_1_Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells.AVI [PDF]
, 2019 Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated.
Felipe Del Valle Batalla (6373913) +4 more
core +1 more source
Dendritic Cells and HIV-1 Trans-Infection
Viruses, 2010 Dendritic cells initiate and sustain immune responses by migrating to sites of pathogenic insult, transporting antigens to lymphoid tissues and signaling immune specific activation of T cells through the formation of the immunological synapse.
David McDonald
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Etude de l'immuno-infiltration et du rôle fonctionnel des lymphocytes T cytotoxiques dans les lymphomes folliculaires [PDF]
, 2012 Le lymphome folliculaire (LF) est le second des lymphomes malins en fréquence. Le LF est une maladie encore considérée comme incurable. Dans ce contexte, l'immuno-intervention est une approche prometteuse dans la mesure où des données cliniques et ...
Laurent, Camille
core
Video_2_Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells.AVI [PDF]
, 2019 Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated.
Felipe Del Valle Batalla (6373913) +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco +7 more
wiley +1 more source