IMGT-NC Engineered Variants of INN Therapeutic IG or Antibodies and Related IgSF Proteins (TR, FPIA and CPCA): Bridging Sequences, Structures and Functions for AI [PDF]
BiomoleculesIMGT®, the international information system® (IMGT), was created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS) in Montpellier, France, to deal with and to manage the huge diversity of immunoglobulins (IG) or antibodies and T-cell ...
Marie-Paule Lefranc
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IMGT® Nomenclature of Immunoglobulins (IG) or Antibodies and T Cell Receptors (TR): A Common Language for Immunoinformatics and Artificial Intelligence (AI) [PDF]
AntibodiesThe immunoglobulins (IG) or antibodies and the T cell receptors (TR) are the antigen receptors of the adaptive immune responses (AIR) of jawed vertebrates (Gnathostomata).
Marie-Paule Lefranc, Gérard Lefranc
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Immunoglobulins: 25 Years of Immunoinformatics and IMGT-ONTOLOGY
Biomolecules, 2014 IMGT®, the international ImMunoGeneTics information system® (CNRS and Montpellier University) is the global reference in immunogenetics and immunoinformatics.
Marie-Paule Lefranc
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Recommendations for HLA Genotyping Data Standards and Clinical Laboratory Staffing Considerations. [PDF]
HLAABSTRACT The rapid advances in HLA genotyping technology and the massive amounts of associated data have created a demand for better and more efficient laboratory data management practices. However, while some standards have been developed, there is a need for comprehensive guidelines that include all laboratory data‐related processes such as messaging,
Spierings E +9 more
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Expanded Allelic Diversity of Non-Classical HLA Class I and MIC Loci Identified Using Full-Gene Hybrid Capture-Based Next-Generation Sequencing. [PDF]
HLAABSTRACT Non‐classical HLA Class I genes (HLA‐E, ‐F, ‐G, ‐H) and MHC‐related genes (MICA, MICB) regulate NK cell function and immune tolerance, yet their allelic diversity remains underexplored. Using capture‐enriched full‐gene sequencing of 943 healthy US transplant donors, we identified 26 novel alleles across HLA‐E (2), HLA‐F (6), HLA‐G (4), HLA‐H ...
Chaaithanya IK +5 more
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Nomenclature for Factors of the HLA System, 2026. [PDF]
HLAHLA, Volume 107, Issue 3, March 2026.
Marsh SGE +14 more
europepmc +2 more sources
Biomolecules, 2022 IMGT®, the international ImMunoGeneTics information system®, created in 1989, by Marie-Paule Lefranc (Université de Montpellier and CNRS), marked the advent of immunoinformatics, a new science which emerged at the interface between immunogenetics and ...
Marie-Paule Lefranc, Gérard Lefranc
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IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors. [PDF]
PLoS ONE, 2015 The adaptive immune responses of humans and of other jawed vertebrate species (gnasthostomata) are characterized by the B and T cells and their specific antigen receptors, the immunoglobulins (IG) or antibodies and the T cell receptors (TR) (up to 2.1012
Safa Aouinti +4 more
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Frontiers in Immunology, 2020 IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics,
Perrine Pégorier +10 more
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IMGT® Biocuration and Analysis of the Rhesus Monkey IG Loci
Vaccines, 2022 The adaptive immune system, along with the innate immune system, are the two main biological processes that protect an organism from pathogens. The adaptive immune system is characterized by the specificity and extreme diversity of its antigen receptors.
Viviane Nguefack Ngoune +10 more
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