Results 201 to 210 of about 491,747 (317)

Durable Interactions of T Cells With T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse

, 2018
Viveka Mayya, Edward Judokusumo, Willie Neiswanger, David Depoil, David A. Blair, Chris H. Wiggins, Lance C. Kam, Michael L. Dustin   +7 more
openalex   +1 more source

High content cell imaging reveals actin cytoskeleton-mediated control of the immunological synapse [PDF]

, 2020
Yolla German
openalex  

LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse [PDF]

, 2009
Xiaodong Zheng, Yanyan Wang, Haiming Wei, Rui Sun, Zhigang Tian   +4 more
openalex   +1 more source

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

Allergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang, Telly Sepahpour, Stephanie Kortchak, Kirthiram Krishnaveni Sivakumar, Spyros Karaiskos, Ngoc Pham, Yura Jang, Montserrat Puig, Michael Norcross   +8 more
wiley   +1 more source

Resolving dynamics of cell signaling via real-time imaging of the immunological synapse.

, 2009
Mark Stevens, Janet R. Pfeiffer, Bridget S. Wilson, Jerilyn A. Timlin, James L. Thomas, Keith A. Lidke, Kathrin Spendier, Janet M. Oliver, Amanda Carroll‐Portillo, Jesse Aaron, Dina T. Mirijanian, Bryan. Carson, Alan R. Burns, Roberto Rebeil   +13 more
openalex   +2 more sources

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Author response: T cell stiffness is enhanced upon formation of immunological synapse

, 2021
Philipp Jung, Xiangda Zhou, Sandra Iden, Markus Bischoff, Bin Qu   +4 more
openalex   +1 more source

Is the tumor cell side of the immunological synapse a polarized secretory domain? [PDF]

Front Immunol
Biolato AM, Filali L, Pereira Fernandes D, Moreau F, Mgrditchian T, Hoffmann C, Thomas C.   +6 more
europepmc   +1 more source

Quantitative Imaging Approaches to Study the CAR Immunological Synapse [PDF]

, 2017
Malini Mukherjee, Emily M. Mace, Alexandre F. Carisey, Nabil Ahmed, Jordan S. Orange   +4 more
openalex   +1 more source