Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
An integrated workflow for phosphopeptide identification in natural killer cells (NK-92MI) and their targets (MDA-MB-231) during immunological synapse formation. [PDF]
STAR Protoc, 2023 Perez-Hernandez D +3 more
europepmc +1 more source
Uncoupling between Immunological Synapse Formation and Functional Outcome in Human γδ T Lymphocytes [PDF]
, 2003 Benoı̂t Favier +6 more
openalex +1 more source
Author response: T cell stiffness is enhanced upon formation of immunological synapse
, 2021 Philipp Jung +4 more
openalex +1 more source
Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe +6 more
wiley +1 more source
Corrigendum: WASp Is Crucial for the Unique Architecture of the Immunological Synapse in Germinal Center B-Cells. [PDF]
Front Cell Dev Biol, 2022 Li Y +4 more
europepmc +1 more source
Resolving dynamics of cell signaling via real-time imaging of the immunological synapse.
, 2009 Mark Stevens +13 more
openalex +2 more sources
The Membrane-Microfilament Linker Ezrin Is Involved in the Formation of the Immunological Synapse and in T Cell Activation [PDF]
, 2001 Anne Roumier +8 more
openalex +1 more source