Results 81 to 90 of about 4,550 (156)

Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages

Antibodies, 2013
Human cytolytic fusion proteins (hCFPs) are comprised of a specific cell-surface-binding moiety and an effector molecule of human origin. In contrast to common immunotoxins, including bacterial or plant toxins, they are considered not to be immunogenic ...
Theo Thepen, Stefan Barth, Rainer Fischer, Michael Huhn, Radoslav Mladenov, Eric Aslanian, Dmitrij Hristodorov, Sonja Schiffer   +7 more
doaj   +1 more source

Dysregulated Expression of Glycolipids in Tumor Cells: From Negative Modulator of Anti-Tumor Immunity to Promising Targets for Developing Therapeutic Agents

Frontiers in Oncology, 2016
Glycolipids are complex molecules consisting of a ceramide lipid moiety linked to a glycan chain of variable length and structure. Among these are found the gangliosides, which are sialylated glycolipids ubiquitously distributed on the outer layer of ...
Jose Luis Daniotti, Ricardo Dante Lardone, Aldo Alejandro Vilcaes   +2 more
doaj   +1 more source

immunotoxin

Citation: 'immunotoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13326 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Clinical Development of Experimental Therapies for Malignant Glioma

Sultan Qaboos University Medical Journal, 2011
Advances in medical and surgical treatments in the last two to three decades have resulted in quantum leaps in the overall survival of patients with many types of non-central nervous system (CNS) malignant disease, while survival of patients with ...
Nikolai G Rainov, Volkmar Heidecke
doaj  

Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. [PDF]

Front Immunol
Kozlíková M, Aukrust IKF, Rohlíčková M, Macháček M, Berg K, Weyergang A, Selbo PK.   +6 more
europepmc   +1 more source

Birinapant selectively enhances immunotoxin-mediated killing of cancer cells conditional on the IAP protein levels within target cells. [PDF]

FASEB J, 2023
Antignani A, Bilotta MT, Roth JS, Urban DJ, Shen M, Hall MD, FitzGerald D.   +6 more
europepmc   +1 more source

Enhanced Antitumor Efficacy of a Combination of Immunotoxin and Photosensitizer Under Illumination in Xenograft Mice. [PDF]

Biomedicines
Hamakubo S, Komatsu N, Kosai A, Kuroda M, Sawada M, Shimizu R, Ohashi R, Suenaga H, Hamakubo T, Abe T.   +9 more
europepmc   +1 more source

An Innovative Immunotoxin Design Against Allergy Based on the IL-33 Cytokine and the Ribotoxin α-Sarcin. [PDF]

Int J Mol Sci
Narbona J, Lázaro-Gorines R, Gutiérrez-Carmona A, López-Rodríguez JC, Villalba M, Lacadena J.   +5 more
europepmc   +1 more source

Immunotoxin [PDF]

, 2020
openaire   +1 more source

GPA33-Targeted Trimeric Immunotoxin Exhibits Enhanced Antitumor Activity in Human Colorectal Cancer Xenografts. [PDF]

Int J Mol Sci
Ruiz-de-la-Herrán J, Narbona J, Gordo RG, Sanz L, Lacadena J.   +4 more
europepmc   +1 more source