Results 51 to 60 of about 7,748 (215)
Cellular Respiration in Thymic Fragments from Mice
Frontiers in Bioscience-Landmark, 2022 Background: This report aims to detail the use of the phosphorescence oxygen analyzer for in vitro investigation of thymic responses to pharmaceutical agents, in particular immunosuppressants and immunomodulators.
Mariam Alshamsi +3 more
doaj +1 more source
Immunotoxin Treatment of Cancer [PDF]
Annual Review of Medicine, 2007 Immunotoxins are proteins used to treat cancer that are composed of an antibody fragment linked to a toxin. The immunotoxin binds to a surface antigen on a cancer cell, enters the cell by endocytosis, and kills it. The most potent immunotoxins are made from bacterial and plant toxins.
Pastan, Ira +3 more
openaire +2 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms
Bioengineering, 2023 Recent advances in targeted cancer therapy hold great promise for both research and clinical applications and push the boundaries in finding new treatments for various currently incurable cancers.
Linxiang Yin, Hatim Thaker
doaj +1 more source
The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer [PDF]
, 2017 CD25 (also termed IL2RA) forms one component of the high‐affinity heterotrimeric interleukin 2 (IL2) receptor on activated T cells. Its affinity for IL2 and cellular function are tightly regulated and vary in different cell types.
Flynn, MJ, Hartley, JA
core +1 more source
eFood, Volume 7, Issue 3, June 2026.Edulitin 2 is a ribotoxin‐like protein exhibiting a potent antiproliferative activity towards Caco‐2 and HT29 cells by programmed cell death. However, edulitin 2 does not affect gut microbiota growth, despite damaging fungal ribosomes. ABSTRACT Porcini (Boletus edulis Bull.) are a reservoir of pharmacological biomolecules with health‐promoting ...
Massimo Bortolotti +11 more
wiley +1 more source
Development of a recombinant antibody to target peptides and proteins to sialoadhesin-expressing macrophages [PDF]
, 2013 Background: Sialoadhesin (Sn)-expressing monocytes/macrophages have been associated with several diseases like inflammatory and autoimmune disorders as well as viral infections, and they also appear to play a role in the initiation of an adaptive immune ...
Delputte, Peter +4 more
core +2 more sources
Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez +4 more
wiley +1 more source
Cancer Immunotherapy and the Immune Response in Hodgkin Lymphoma
Frontiers in Oncology, 2018 Patients with classical Hodgkin lymphoma (cHL) have an impaired cellular immune response as indicated by an anergic reaction against standard recall antigens and a diminished rejection reaction of allogeneic skin transplant. This clinical observation can
Christoph Renner, Frank Stenner
doaj +1 more source
Technology and Biological Weapons: Future Threats [PDF]
, 2004 Ye
Davison, N., Millett, P., Nixdorff, K.
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