Results 51 to 60 of about 114,834,543 (300)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Release of nutrients and exorphins during in vitro static gastrointestinal digestion of spaghetti from durum wheat

, 2014
Consumption of wheat-derived products has been linked with significant nutritional and health impacts such as the management of glycaemic index and the onset of immunological reactions.
A. Marti, V. Micard, S. Cattaneo, A. Ferraretto, P. De Luca, M.A. Pagani, I. De Noni, M. Stuknyte   +7 more
core   +2 more sources

In Vitro Assessment of the Physiologically Relevant Oral Bioaccessibility of Metallic Elements in Edible Herbs Using the Unified Bioaccessibility Protocol

Molecules, 2023
In this work, the total content of seven metallic elements (Fe, Cu, Zn, Mg, Pb, Ni, and Co) in common edible herbs was determined and related to their bioaccessibility by an in vitro human digestion model.
Tatiana G. Choleva, Charikleia Tziasiou, Vasiliki Gouma, Athanasios G. Vlessidis, Dimosthenis L. Giokas   +4 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Evaluation of bioaccessibility of bioactive compounds in ready-to-eat refrigerated and frozen broccoli using in vitro digestion models

Scientific Reports
Refrigerated and frozen ready-to-eat cooked vegetables are becoming increasingly popular with consumers and catering services. Simulating digestion is essential for accurately assessing the nutritional value of ready-to-eat vegetables, as raw composition
Mohamed Awad Abd Allah, Ghada Khiralla, Hesham Elhariry   +2 more
doaj   +1 more source

Peptidomic data of egg white gastrointestinal digests prepared using the Infogest Harmonized Protocol

Data in Brief, 2020
These data are related to the research article entitled “Induction of CCK and GLP-1 release in enteroendocrine cells by egg white peptides generated during gastrointestinal digestion”. In this article, the peptide and free amino acid profile of egg white
Marta Santos-Hernández, Beatriz Miralles, Lourdes Amigo, Isidra Recio   +3 more
doaj   +1 more source

Atividade antioxidante e crioconcentração dos compostos bioativos do extrato aquoso de erva-mate (Ilex paraguariensis A. St. Hil.) [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2015.A atividade antioxidante do extrato aquoso de erva-mate está relacionada principalmente ...
Boaventura, Brunna Cristina Bremer
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A review of in-vitro digestibility models on diverse foods in various segments of human digestive tract

Discover Food
In order to simulate the process of food digestion in the gastrointestinal (GI) tract, various in-vitro digestion models have been developed. These models vary from simple, single-compartment systems to more complex setups with multiple compartments and ...
B. Shiva Kiran, Omar Bashir, Prashant Anil Pawase, Kshirod Kumar Dash, Tawheed Amin, Rafeeya Shams, Ayaz Mukarram Shaikh, Kovács Béla   +7 more
doaj   +1 more source

Amino acids release from enriched bread with edible insect or pea protein during in vitro gastrointestinal digestion [PDF]

, 2021
[EN] The aim of this study was to investigate the amino acid (AA) release from breads enrichment with edible insects, Alphitobius diaperinus and Tenebrio molitor or pea protein during in vitro gastrointestinal digestion.
Igual Ramo, Marta, García-Segovia, Purificación, Martínez-Monzó, Javier   +2 more
core   +1 more source