Results 91 to 100 of about 114,819,952 (302)

Beneficial efficacy of various propolis extracts and their digestive products by in vitro simulated gastrointestinal digestion

open access: yesLWT, 2017
Abstract Propolis is a waxy substance from many plant material which is rich in polyphenols with numerous biological activities. The current experiment was designed to assess the antioxidant and cyclooxygenase-2 (COX-2) inhibitory activities of various propolis extracts and their digestive products on human oral carcinoma KB cells.
Chi-Hua Yen   +7 more
openaire   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Effect of simulated gastrointestinal digestion in vitro on the antioxidant activity of Semen ziziphi spinosae protein hydrolysates

open access: yes, 2021
Objective: In this study, semen ziziphi spinosae protein hydrolysates (SZPHs) with good antioxidant activity were used as the research object. Methods: By simulating gastrointestinal digestion in vitro, the semen ziziphi spinosae protein hydrolysates ...
Hong-yin, ZHANG   +6 more
core   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

open access: yesAdvanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang   +3 more
wiley   +1 more source

Rapid start-up of thermophilic anaerobic digestion with the turf fraction of MSW as inoculum [PDF]

open access: yes, 2011
This study aims to determine suitable start-up conditions and inoculum sources for thermophilic anaerobic digestion. Within days of incubation MSW at 55°C, methane was produced at a high rate.
Suwannoppadol, S.   +2 more
core  

Correction to Environmental Impact of ZnO Nanoparticles Evaluated by in Vitro Simulated Digestion

open access: yes, 2020
This is a corrigendum to the original article "Environmental impact of ZnO nanoparticles evaluated by in vitro simulated digestion" that was published in the journal "ACS Applied Nano Materials", vol. 3 (2020), no. 1, pp.
Thünemann, Andreas   +15 more
core   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

open access: yesAdvanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun   +13 more
wiley   +1 more source

Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix

open access: yes, 2022
The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process.
Žakula, Jelena   +8 more
core   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang   +9 more
wiley   +1 more source

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