Probing the Biological Plausibility of Fluoride as an Endocrine Disruptor
Birth Defects Research, Volume 118, Issue 5, May 2026.ABSTRACT Background Fluoride has come under recent scrutiny regarding concerns over potential neurodevelopmental and endocrine‐related toxicities, with recent reviews by the National Toxicology Program (NTP) and European Food Safety Authority (EFSA) concluding with moderate or reasonable confidence, respectively, that exposure to drinking water having ...
Ashley M. Mudd +2 more
wiley +1 more source
A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. [PDF]
, 2019 Testis-expressed X-linked genes typically evolve rapidly. Here, we report on a testis-expressed X-linked microRNA (miRNA) cluster that despite rapid alterations in sequence has retained its position in the Fragile-X region of the X chromosome in ...
Cook-Andersen, Heidi +12 more
core
RNA Modifications: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 5, May 2026.Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Mini Bioreactor Can Support In Vitro Spermatogenesis of Mouse Testicular Tissue. [PDF]
Cell J, 2022 Amirkhani Z +3 more
europepmc +1 more source
Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro [PDF]
, 2004 Spermatogonia are the male germ stem cells that continuously produce sperm for the next generation. Spermatogenesis is a complicated process that proceeds through mitotic phase of stem cell renewal and differentiation, meiotic phase, and postmeiotic ...
Chen, TS +9 more
core
Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities
MedComm, Volume 7, Issue 5, May 2026.This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng +8 more
wiley +1 more source
High‐Resolution Imaging Reveals Mitochondrial Protein Imbalance in Sperm of Oligoasthenospermic Men
Molecular Reproduction and Development, Volume 93, Issue 5, May 2026.ABSTRACT Male infertility accounts for nearly half of global infertility cases and is often linked to poor sperm quality, such as oligospermia, asthenospermia, and teratospermia. Although the exact mechanisms remain unclear, mitochondria, which are critical for ATP production and reactive oxygen species generation during fertilization, are increasingly
Pauline Teixeira +8 more
wiley +1 more source
Exposing dairy bulls to high temperature-humidity index during spermatogenesis compromises subsequent embryo development in vitro [PDF]
, 2020 Broekhuijse, Marleen L.W.J. +10 more
core +2 more sources
Use of Pentoxifylline to Improve Seminal Parameters in Dogs
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.A single oral dose of pentoxifylline (10 mg/kg) administered 40 min before ejaculation significantly improved sperm concentration and progressive motility in dogs. The effect was most pronounced in oligospermic subjects, supporting pentoxifylline as a rapid, well‐tolerated adjunct therapy for canine subfertility .
Vincenzo Cicirelli +6 more
wiley +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, Volume 14, Issue 4, Page 1002-1016, May 2026.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source