Results 41 to 50 of about 27,781 (266)
In vivo and in vitro evaluation of betanine mutagenicity.
CYTOLOGIA, 1990 Information about the mutagenic effect of natural food colors gives scientific support to their use as food additives. Two different forms of beet root colours were tested: form I without nitrate residues and form II with nitrate residues. Mutagenic effects were tested in vitro using the human peripheral blood lymphocyte system and in vivo using the ...
2-Froes, Nivea +2 more
openaire +3 more sources
Genetics and Molecular Biology, 2005 Cashew (Anacardium occidentale) is a medicinal plant native to Brazil and also yields a nutritious fruit juice. Its large pulpy pseudo-fruit, referred to as the cashew apple, contains high concentrations of vitamin C, carotenoids, phenolic compounds and ...
Ana Amélia Melo Cavalcante +4 more
doaj +1 more source
Review of pyronaridine anti-malarial properties and product characteristics. [PDF]
, 2012 Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J +7 more
core +2 more sources
An Ensemble Model of QSAR Tools for Regulatory Risk Assessment [PDF]
, 2016 Quantitative structure activity relationships (QSARs) are theoretical models that relate a quantitative measure of chemical structure to a physical property or a biological effect.
Merrill, Stephen +3 more
core +4 more sources
An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract. [PDF]
J Appl ToxicolABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
Weston JK, Lynch BS, Akingbasote JA.
europepmc +2 more sources
Oxazepam is mutagenic in vivo in Big Blue(R) transgenic mice [PDF]
Carcinogenesis, 1999 Although oxazepam (Serax), a widely used benzodiazepine anxiolytic, does not induce gene mutations in vitro or chromosomal aberrations in vivo, it was found to be a hepatocarcinogen in a 2 year bioassay in B6C3F1 mice. Thus, it was of interest to determine whether this carcinogen is mutagenic in vivo.
B S, Shane +3 more
openaire +2 more sources
Mutagenicity and teratogenicity studies of vitacoxib in rats and mice
Toxicology Reports, 2018 Vitacoxib is a new drug candidate for treatment of inflammation, pain and fever as selective cyclooxygenase-2 inhibitors. In the current study, the mice sperm abnormality, mammalian erythrocyte micronucleus and in vivo chromosome aberration, and ...
Jianzhong Wang +5 more
doaj +1 more source
Genotoxicity test of eight natural color additives in the Korean market
Genes and Environment, 2022 Background Various natural color additives are preferred by many consumers over synthetic color additives because they are perceived to be safer. However, most do not have sufficient toxicity data for safety assurance.
Byungkyung Do, Hoonjeong Kwon
doaj +1 more source
Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet [PDF]
, 2011 Peer reviewedPublisher ...
Hani eEl-Nezami +3 more
core +4 more sources
In Vivo Mutagenic Effect of Very Low Dose Radiation
Dose-Response, 2006 Almost all of our knowledge about the mutational effect of radiation has come from high dose studies which are generally not relevant to public exposure. The pKZ1 mouse recombination mutagenesis assay enables study of the mutational effect of very low doses of low LET radiation (μGy to cGy range) in a whole animal model.
Sykes, Pamela J +6 more
openaire +4 more sources