Results 61 to 70 of about 27,055 (211)

Evaluation of extracts from Coccoloba mollis using the Salmonella/microsome system and in vivo tests [PDF]

, 2010
The common everyday use of medicinal plants is an ancient, and still very widespread practice, whereby the need for studies on their possible toxicity and mutagenic properties.
TSUBOY, Marcela Stefanini, MARCARINI, Juliana Cristina, FERREIRA, Dalva Trevisan, FERRAZ, Elisa Raquel Anastácio, CHEQUER, Farah Maria Drumond, OLIVEIRA, Danielle Palma de, RIBEIRO, Lúcia Regina, MANTOVANI, Mário Sérgio   +7 more
core   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Epigenetic Effects of Polybrominated Diphenyl Ethers on Human Health. [PDF]

, 2019
Disruption of epigenetic regulation by environmental toxins is an emerging area of focus for understanding the latter's impact on human health. Polybrominated diphenyl ethers (PBDEs), one such group of toxins, are an environmentally pervasive class of ...
Poston, Robert G, Saha, Ramendra N
core   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Application of micronucleus assay in plants to monitor environmental pollution in situ [PDF]

, 2008
Samples of 5 vascular plant species: Achillea millefolium L., Artemisia vulgaris L., Festuca gigantea (L.) VILL., Ranunculus acris L. s. str. and Vicia angustifolia L. were collected near Fuel Storage Station, Chemical Fibre Factory “Wistom” in Tomaszów
Kośmider, Beata, Osiecka, Regina, Siciński, Jan T.   +2 more
core  

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

Environmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves, Matheus Mantuanelli Roberto, Adriana Fabiana Corrêa da Silva, Maria Aparecida Marin‐Morales   +3 more
wiley   +1 more source

Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques. [PDF]

Genes Environ, 2023
Izawa K, Tsuda M, Suzuki T, Honma M, Sugiyama KI.   +4 more
europepmc   +1 more source

The Employment of Hydrogen Peroxide in Water Disinfection Poses a Threat to Aquatic Ecosystems Because of Its Toxicity to Nontarget Organisms

Environmental Toxicology, EarlyView.
ABSTRACT Hydrogen peroxide is widely used in water and wastewater treatment, particularly in advanced oxidation processes that aid in the degradation of compounds and microbial disinfection. Despite concerns about potential environmental contamination, its impact on freshwater ecosystems remains inadequately studied.
Letícia Queiroz Almeida, Thayrine Dias Carlos, Leydiane Barbosa Bezerra, Rone S. Barbosa, Nelson Luís Gonçalves Dias Souza, Douglas Henrique Pereira, Renato Almeida Sarmento, Grasiele Soares Cavallini   +7 more
wiley   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse. [PDF]

Genes Environ, 2023
Murata Y, Suzuki K, Shigeta Y, Iso T, Hirose N, Umano T, Horibata K, Sugiyama KI, Hirose A, Masumura K, Matsumoto M.   +10 more
europepmc   +1 more source