Results 71 to 80 of about 4,853 (196)

Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC

open access: yesMolecules, 2017
Indirubin is an active component of the herbal ingredient ‘Danggui Longhui wan’, which was used for the treatment of inflammation and chronic myeloid leukemia in China.
Jana Tegethoff   +5 more
doaj   +1 more source

Biocomputational Screening of Natural Compounds against Acetylcholinesterase

open access: yesMolecules, 2021
Alzheimer’s disease (AD) is the most common form of dementia and is characterized by irreversible and progressive neurodegeneration. Cholinergic dysfunction has been reported in AD, and several cholinesterase inhibitors, including natural compounds and ...
Syed Sayeed Ahmad   +6 more
doaj   +1 more source

An Improved Method for the Large-Scale Processing of Woad (Isatis tinctoria) for Possible Commercial Production of Woad Indigo [PDF]

open access: yes, 1998
The increasing use of alternative crops has meant the introduction of new technologies to process their products. In this work, an alternative method is presented for the extraction of natural indigo from woad (Isatis tinctoria) based on a technique used
Cooke, DT, Gilbert, Kerry, Hill, DJ
core   +2 more sources

Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential

open access: yesBiomolecules, 2021
Oximes have been studied for decades because of their significant roles as acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have been reported with useful pharmaceutical properties, including compounds with ...
Igor A. Schepetkin   +4 more
doaj   +1 more source

Synthesis and biological evaluation of anti-Toxoplasma gondii activity of a novel scaffold of thiazolidinone derivatives [PDF]

open access: yes, 2017
We designed and synthesised novel N-substituted 1,3-thiazolidin-4-one derivatives for the evaluation of their anti-Toxoplasma gondii efficacy. This scaffold was functionalised both at the N1-hydrazine portion with three structurally different moieties ...
Bizzarri, Bruna   +9 more
core   +1 more source

Alternative natural sources of indirubin derivatives [PDF]

open access: yes, 2021
Indirubins are bis-indole alkaloid compounds occurring naturally in various indigocontainingplants and mollusk gastropods. These molecules were initially known fortheir long history in the dye industry. However, during the last two decades, thechemical and biological studies of indirubins have increased tremendously due to thediscovery of their bio ...
openaire   +1 more source

Cytotoxic activity of Isatis campylocarpa, an Iranian endemic plant, on human cancer cell lines [PDF]

open access: yesJournal of Cell and Molecular Research, 2009
The antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of Isatis campylocarpa an endemic species of the Brassicaceae family from Iran, investigated on the growth of Jurkat as an acute lymphocytic leukemia cell line,
Sasan Mohsenzadeh   +3 more
doaj   +1 more source

Gene Expression Omnibus database analysis reveals comorbidity mechanisms of type 2 diabetes mellitus and vascular dementia and predicts potential herbal therapeutics

open access: yesAdvanced Chinese Medicine, Volume 2, Issue 4, Page 147-162, December 2025.
Abstract Objective This study aimed to investigate the comorbid mechanisms linking type 2 diabetes mellitus (T2DM) and vascular dementia (VaD), focusing on the roles of astrocytes and neurons, and to identify potential therapeutic traditional Chinese medicines (TCMs) and compounds.
Meiyue Li   +5 more
wiley   +1 more source

BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis [PDF]

open access: yes, 2017
Background: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and ...
Bruno, Pierdonato   +8 more
core   +1 more source

A systematic review of natural colourants and trend forecasting practices for the textile and fashion industry

open access: yesColoration Technology, Volume 141, Issue 6, Page 801-827, December 2025.
Abstract Recent global interest in sustainable practices in the textile and fashion industry has inspired stakeholders to readopt natural colourants. However, integrating these practices raises several questions regarding the latest developments in natural colourant and trend forecasting practices in the textile and fashion industry.
Bintan Titisari, Pammi Sinha
wiley   +1 more source

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