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Mechanisms and Therapeutic Potential of Key Anti-inflammatory Metabiotics: Trans-Vaccenic Acid, Indole-3-Lactic Acid, Thiamine, and Butyric Acid

Probiotics and Antimicrobial Proteins
Identifying metabolites produced by probiotic bacteria, also known as metabiotics, is becoming increasingly common due to their anti-inflammatory, anti-obesogenic, and immunomodulatory effects. Postbiotics alongside diet, regulate both physical and mental health, as the microbiota members can interact physically with host cells or through secretion of ...
Muñoz-Olivos Cristina   +5 more
openaire   +2 more sources

Conversion of Tryptophan, Indole-3-Pyruvic Acid, Indole-3-Lactic Acid and Indole to Indole-3-Acetic Acid by Azospirillum brasilense Sp7

1995
The free-living nitrogen-fixing soil bacterium Azospirillum brasilense Sp7 produces indole-3-acetic acid (IAA) from tryptophan (Trp). Ammonia and oxygen are involved in the processes of IAA production and nitrogen fixation. Oxygen is required during the conversion of Trp to IAA via indole-3-acetamide (IAM).
Tami Bar, Yaacov Okon
openaire   +1 more source

Bifidobacterium bifidum 1007478 derived indole-3-lactic acid alleviates NASH via an aromatic hydrocarbon receptor-dependent pathway in zebrafish

Life Sciences
This study investigates the potential of Bifidobacterium bifidum 1007478 (BB478) and its metabolite indole-3-lactic acid (ILA) in alleviating non-alcoholic steatohepatitis (NASH) induced by a high-fat diet (HFD) and fructose exposure.A zebrafish model of NASH was established by exposure to HFD and fructose.
Lai Wei
exaly   +3 more sources

Electrochemical sensor featuring PdFeCo1−xONPs on carbon paper for the sensitive determination of indole-3-lactic acid levels in serum samples

Talanta
A highly sensitive and selective electrochemical sensing platform with self-assembled porous 3-D trimetallic (Pd, Fe, and Co) hybrid anchored on a cost-effective and high-conducting carbon paper (CP) synthesized via a facile and cost-effective hydrothermal impregnation and thermal reduction technique was developed for determining indole-3-lactic acid ...
Dhananjaya Merum   +2 more
exaly   +3 more sources

Indole-3-lactic acid derived from tryptophan metabolism promotes trophoblast migration and invasion by activating the AhR/VCAN pathway

Placenta
Preeclampsia (PE) is a life-threatening condition that is unique to human pregnancy, and it is a leading cause of maternal and neonatal morbidity and mortality. Currently, the only definitive treatment for PE is delivery of the placenta. Several studies have suggested that the gut microbiota and its derived metabolites may be associated with PE.
Yingying Wei   +7 more
openaire   +2 more sources

Room Temperature Phosphorescence Characteristics of Indole-3-Propionic Acid, DL-Indole-3-Lactic Acid, and Indole-3-Glycolic Acid on Low-Background Paper Substrate

Microchemical Journal, 1995
Room temperature phosphorescence characteristics of indole-3-propionic acid, DL-indole-3-lactic acid, and indole-3-glycolic acid were studied on a low-background paper substrate. The influence of potassium iodide, thallium (I) nitrate, silver (I) nitrate, and lead (II) acetate on the intensities of the analyte signals was evaluated.
J. Deribamar, A.D. Campiglia
openaire   +1 more source

Schizophyllum commune polysaccharide ameliorates diet-induced obesity by regulating the Faecalibaculum rodentium/indole-3-lactic acid/microRNA axis

Carbohydrate Polymers
Diet-induced metabolic disorder is a global health concern, and bioactive polysaccharides have been shown to mitigate metabolic disorder by modifying gut microbiota. Polysaccharides from Schizophyllum commune have shown excellent anti-obesity effects, but the specific regulatory mechanisms remain unclear.
Chaomin, Yin   +8 more
openaire   +2 more sources

[Astragalus polysaccharides improve adipose tissue aging in naturally aged mice via indole-3-lactic acid].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Plant polysaccharides are effective components that widely present in traditional Chinese medicine(TCM), exhibiting rich biological activities. However, as most plant polysaccharides cannot be directly absorbed and utilized by the human digestive system, it is now believed that their mode of action mainly involves interaction with intestinal microbiota,
Yi-Yang, Bao   +8 more
openaire   +1 more source

An engineered Escherichia coli Nissle 1917 increase the production of indole lactic acid in the gut

FEMS Microbiology Letters, 2023
Mikael Pedersen   +2 more
exaly  

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