Results 91 to 100 of about 31,469 (239)

Electrophilic carbonyl activation: competing condensative cyclizations of tryptamine derivatives [PDF]

, 2014
A series of tryptamine derived bisindole substrates were subjected to electrophilic activation of the func-tional grouping at their [alpha]-nitrogen in the form of iminium ions to enable cyclization onto the sterically hindered indole substructure.
Liu, Fan, Movassaghi, Mohammad
core   +1 more source

Mitotic Block of Human Blood Cells by Vinca herbacea, Catharanthus roseus and Colchicine Alkaloids [PDF]

Journal of Medicinal Plants and By-products, 2018
Catharanthus roseus (L.) G.Don is a plant which produces anticancer and anti-mitotic indole alkaloids. Colchicine is an anti-mitotic drug. Anti-mitotic effects of Vinca herbacea Waldst. & Kit. indole alkaloids is unknown.
Babak Delnavaz Hashemloian, Azra Ataei Azimi   +1 more
doaj  

Formation of Nudicaulins In Vivo and In Vitro and the Biomimetic Synthesis and Bioactivity of O-Methylated Nudicaulin Derivatives

Molecules, 2018
Nudicaulins are yellow flower pigments accounting for the color of the petals of Papaver nudicaule (Papaveraceae). These glucosidic compounds belong to the small group of indole/flavonoid hybrid alkaloids.
Bettina Dudek, Florian Schnurrer, Hans-Martin Dahse, Christian Paetz, Anne-Christin Warskulat, Christiane Weigel, Kerstin Voigt, Bernd Schneider   +7 more
doaj   +1 more source

Reprogramming of Gene Transcripts and Metabolites by the Wild Soybean Endophyte Pseudomonas sp. 77S3 Improves Soybean Salt Tolerance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Soybean is a critical source of protein and vegetable oil worldwide. Expanding its cultivation into salinity lands represents a promising strategy for increasing production; however, soil salinity severely limits soybean growth by disrupting physiological and metabolic homeostasis.
Wanying Zhang, Chengyang Song, Tianqi Wang, Xiulin Liu, Yisheng Fang, Zhu Yan, Yaxi Zhu, Na Zheng, Xiaofei Ma, Guochen Qin, Dan Zhu, Junchuan Xiao, Xing Wang Deng, Xiao Luo   +13 more
wiley   +1 more source

Fungal Origins of the Bicyclo[2.2.2]diazaoctane Ring System of Prenylated Indole Alkaloids [PDF]

, 2012
Over eight different families of natural products, consisting of nearly seventy secondary metabolites, which contain the bicyclo[2.2.2]diazaoctane ring system, have been isolated from various Aspergillus, Penicillium, and Malbranchea species. Since 1968,
Antia B. S., Arai K., Baldas J., Banks R. M., Banks R. M., Birch A. J., Birch A. J., Birch A. J., Blanchflower S. E., Blanchflower S. E., Boysen M., Byung H. L., Capon R. J., Chu Y.-S., David H. Sherman, Davies J., Ding Y., Ding Y., Ding Y., Domingo L. R., Figueroa M., Figueroa M., Finefield J. M., Frisvad J. C., Frisvad J. C., Frisvad J. C., Frisvad J. C., Frisvad J. C., Frisvad J. C., Frisvad J. C., Gray C. R., Greshock T. J., Greshock T. J., Greshock T. J., Greshock T. J., Grubbs A. W., Guo J.-P., Hayashi H., Hayashi H., Houbraken J., Houbraken J., Houbraken J., Houbraken J., Houbraken J., Jennifer M. Finefield, Jens C. Frisvad, Kaminsky R., Kato H., Kito K., Kuo M. S., Kuo M. S., Kushida N., Lee B. H., Liesch J. M., Lin Z., Little P. R., Lopez-Gresa M. P., Love S., Martínez-Luis S., Marínez-Luis S., McAfoos T. J., Miller K. A., Miller K. A., Miller K. A., Miller K. A., Mugishima T., Myers A. G., Nielsen K. F., Nielsen K. F., Nielsen K. F., Noonim P., Ondeyka J. G., Ostlind D. A., O’Brien M., Pareniková L., Paterson R. R. M., Paterson R. R. M., Perrone G., Pitt J. I., Polonsky J., Porter A. E. A., Prangé T., Qian-Cutrone J., Raper K. B., Raper K. B., Robbers J. E., Robert M. Williams, Samson R. A., Samson R. A., Samson R. A., Samson R. A., Sanz-Cervera J. F., Scott P. M., Shoop W. L., Steyn P. S., Steyn P. S., Steyn P. S., Stocking E. M., Stocking E. M., Stocking E. M., Stocking E. M., Stocking E. M., Stocking E. M., Stocking E. M., Sugie Y., Sunderhaus J. D., Sørensen A., Tsuda M., Tsukamoto S., Tsukamoto S., Tsukamoto S., Tsukamoto S., Tuthill D. E., Varga J., Watts K. R., Whyte A. C., Williams R. M., Williams R. M., Williams R. M., Williams R. M., Wilson B. J., Wulff J. E., Yamazaki M., Zhang D., Zinser E. W.   +124 more
core   +1 more source

The Potential of Indole Alkaloids in Bone Health and Osteoporosis Management

Applied Sciences
Indole alkaloids, a class of plant-derived nitrogen-containing compounds, have emerged as promising candidates for osteoporosis treatment. Their favorable biocompatibility profile demonstrated efficacy in preclinical models, and low reported toxicity ...
Anna Caruso, Virginia Caira, Hussein El-Kashef, Carmela Saturnino   +3 more
doaj   +1 more source

New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata

Natural Products and Bioprospecting, 2019
Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3–10), were isolated from the twigs and leaves of ...
Xiang-Mei Li, Xian-Jun Jiang, Guo-Zhu Wei, Li-Hua Ren, Li-Xia Wang, Xue-Lian Cheng, Fei Wang   +6 more
doaj   +1 more source

Auxin‐Induced Nicotine Inhibition Is Mediated by NaARF5 Through the Suppression of NaERF1‐Like Expression and Interaction With NaERF1‐Like in Nicotiana attenuata

Plant Biotechnology Journal, EarlyView.
ABSTRACT Nicotine is the most abundant alkaloid produced by Nicotiana species against insect herbivores. Although it has been known for decades that auxin can strongly inhibit nicotine biosynthesis, the underlying mechanisms have remained unclear.
Miyun Yang, Ahui Tong, Lei Wang, Jinsong Wu   +3 more
wiley   +1 more source

Studies towards the Total Asymmetric Synthesis of the Pentacyclic Indole Alkaloid Arboflorine: Asymmetric Synthesis of a Key Intermediate [PDF]

, 2011
The synthesis of a plausible key intermediate for a biomimetic asymmetric synthesis of indole alkaloid arboflorine is described. The method featured the use of Ellman's sulfinamide chemistry for the establishment of the first chiral center, and the ...
Du, Yu, Huang, Hui-Ying, Huang, Pei-Qiang, Liu, Hui, Ruan, Yuan-Ping, 阮源萍, 黄培强   +6 more
core   +1 more source

Acute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats

Natural Products and Bioprospecting, 2020
Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated.
Yun-Li Zhao, Min Su, Jian-Hua Shang, Xia Wang, Guy Sedar Singor Njateng, Guang-Lei Bao, Jia Ma, Qing-Di Sun, Fang Yuan, Jing-Kun Wang, Xiao-Dong Luo   +10 more
doaj   +1 more source