Results 251 to 260 of about 166,084,760 (290)
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New Heteroarylbenzenesulfonamides as Matrix Metalloproteinase Inhibitors.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Frédéric, Delbecq   +4 more
openaire   +2 more sources

Selective matrix metalloproteinase inhibitors

2017
The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The compounds can be selective MMP inhibitors, for example, selective inhibitors of MMP-2, MMP-9, and/or MMP-14. The disease, disorder, or condition can include, for example, stroke,
CHANG MAYLAND, MOBASHERY SHAHRIAR
openaire   +6 more sources

The Regulation of Neovascularization by Matrix Metalloproteinases and Their Inhibitors

STEM CELLS, 1997
The process of new capillary formation from preexisting vessels, angiogenesis, is a complex physiological event which is strictly controlled, occurring only very rarely under normal conditions. In contrast, there are a number of serious diseases, among them solid tumor growth, rheumatoid arthritis and several eye diseases, which are characterized by ...
openaire   +2 more sources

Matrix Metalloproteinase Inhibitors in Arthritis

Journal of Enzyme Inhibition, 1998
K M, Bottomley   +2 more
openaire   +2 more sources

The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

International Journal of Molecular Sciences, 2020
Claudia Castruita-De la Rosa   +2 more
exaly  

Matrix metalloproteinases inhibitors in idiopathic pulmonary fibrosis: Medicinal chemistry perspectives

European Journal of Medicinal Chemistry, 2021
Liang Ouyang, Guan Wang, Tinghong Ye
exaly  

Matrix metalloproteinases and their inhibitors.

Anticancer research, 1999
Degradation of the extracellular matrix around tumour cells is an essential step in the process of tumour invasion and metastasis. The family of structurally related metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinases (TIMP), play an important role in matrix degradation by tumour cells. In this paper MMP and TIMP
openaire   +1 more source

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