Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neuronsin vitro [PDF]
The characteristics of long-duration inhibitory postsynaptic potentials (1-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from an in vitro slice preparation. Stimulation with suprathreshold intensities evoked 1-IPSPs with typical durations of 600-900 msec at ...
James R. Howe+2 more
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Glutamate-gated chloride channel receptors (GluClRs) mediate inhibitory neurotransmission at invertebrate synapses and are primary targets of parasites that impact drastically on agriculture and human health.
Mohammed Atif+7 more
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Heterosynaptic Regulation of α2A-Adrenoceptors on Glutamate/GABA Release in the Prefrontal Cortex of Rats [PDF]
Background/Objectives: Norepinephrine (NE) plays a crucial role in modulating cognitive processes via α2A-adrenoceptors (α2A-ARs) within the prefrontal cortex (PFC), an essential brain region responsible for higher cognitive functions.
Yaru Wei+5 more
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Effect of standing posture on inhibitory postsynaptic potentials in gastrocnemius motoneurons [PDF]
This study examined the task dependence of sensory inputs on motoneuron excitability by comparing the inhibitory postsynaptic potential (IPSP) evoked by stimulation of the sural nerve between a standing postural task (Free Standing) and a comparable voluntary isometric contraction performed in a supine position (Lying Supine).
S. Jayne Garland+3 more
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Gamma-hydroxybutyrate Reduces GABAA-mediated Inhibitory Postsynaptic Potentials in the CA1 Region of Hippocampus [PDF]
Gamma-hydroxybutyric acid (GHB) is a psychoactive drug and a putative neurotransmitter, derived from gamma-aminobutyric acid (GABA). At micromolar concentrations GHB binds to specific high and low affinity binding sites present in discrete areas of the brain, while at millimolar concentrations GHB also binds to GABA(B) receptors.
Maurizio Cammalleri
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Electrogenesis of the slow inhibitory postsynaptic potential in bullfrog sympathetic ganglia.
The ionic mechanisms of the slow surface positive (P)-potential and the slow inhibitory postsynaptic potential (IPSP), an intracellularly recorded P-potential in sympathetic ganglia, were analysed by means of sucrose-gap, intracellular microelectrode techniques, and voltage clamp technique.
Takashi Akasu, K. Koketsu
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Effects of Methylphenidate on the Inhibitory Postsynaptic Potential in Rat Locus Coeruleus Neurons.
Effects of methylphenidate (MPH), an agent used clinically for the treatment of children presenting the attention-deficit/hyperactivity disorder (AD/HD), on synaptic transmission in the rat locus coeruleus (LC) were examined by intracellular recording methods.
Takashi Kuwahata+3 more
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Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat [PDF]
Adenosine is a depressant in the central nervous system with pre‐ and postsynaptic effects. In the present study, intracellular recording techniques were applied to investigate the modulatory effects of adenosine on projection neurons in the lateral rat amygdala (LA), maintained as slices in vitro. Adenosine reversibly reduced the amplitude of a fast
Thomas Heinbockel, Hans‐Christian Pape
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Inhibitory Postsynaptic Potentials Carry Synchronized Frequency Information in Active Cortical Networks [PDF]
Temporal precision in spike timing is important in cortical function, interactions, and plasticity. We found that, during periods of recurrent network activity (UP states), cortical pyramidal cells in vivo and in vitro receive strong barrages of both excitatory and inhibitory postsynaptic potentials, with the inhibitory potentials showing much higher ...
Andrea R. Hasenstaub+5 more
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Effects of milnacipran (MIL), a serotonin and noradrenaline reuptake inhibitor (SNRI), on synaptic transmission were examined in the rat locus coeruleus (LC). Bath-application of MIL produced a hyperpolarization associated with a decrease in input resistance of LC neurons.
Takashi Kuwahata+3 more
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