Results 31 to 40 of about 1,498,031 (298)
Frontiers in Immunology, 2023 Natural killer (NK) cells play an important role in the early defense against tumors and virally infected cells. Their function is thought to be controlled by the balance between activating and inhibitory receptors, which often compete for the same ...
Vanna Imširović +4 more
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Mast cell inhibitory receptors
Postępy Higieny i Medycyny Doświadczalnej, 2012 Mast cells play an important role in diverse physiological mechanisms as well as taking part in antimicrobial defense. What is more, these cells are important regulators of a number of pathophysiological processes, involving allergic reactions. Therefore, it seems to be very important to know and understand the factors and receptors influencing mast ...
Edyta, Bąbolewska +1 more
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THE INHIBITORY EFFECT OF GALLAMINE ON MUSCARINIC RECEPTORS [PDF]
British Journal of Pharmacology, 1976 The inhibitory effect of gallamine (1.1 μM‐1.1 mM) on negative inotropic responses to acetylcholine (ACh) or carbachol (CCh) was investigated in isolated electrically stimulated atria of the guinea‐pig. Gallamine caused parallel rightward shifts of the dose‐response curves to the agonists, with no depression of the maximal response.Gallamine (0.11‐1.1 ...
A L, Clark, F, Mitchelson
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Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-laboring myometrium [PDF]
, 2013 The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been shown to alter spontaneous ...
McMorrow, Jason P. +10 more
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Frontiers in Immunology, 2019 Natural killer (NK) cell function is regulated by a balance between activating and inhibitory receptors, but the details of this receptor interplay are not extensively understood.
Sridharan Ganesan +2 more
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Regulatory Mechanisms and Reversal of CD8+T Cell Exhaustion: A Literature Review
Biology, 2023 CD8+T cell exhaustion is a state of T cell dysfunction during chronic infection and tumor progression. Exhausted CD8+T cells are characterized by low effector function, high expression of inhibitory receptors, unique metabolic patterns, and altered ...
Wanwan Zhu +3 more
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Frontiers in Cellular Neuroscience, 2019 In the adult brain GABAA receptors (GABAARs) mediate the majority of synaptic inhibition that provides inhibitory balance to excitatory drive and controls neuronal output.
Jingjing Duan +8 more
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Molecular Pain, 2010 Background NMDA receptors expressed by spinal cord neurons in the superficial dorsal horn are involved in the development of chronic pain associated with inflammation and nerve injury. The superficial dorsal horn has a complex and still poorly understood
MacDermott Amy B +3 more
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Probing GABAA receptors with inhibitory neurosteroids
Neuropharmacology, 2018 γ-aminobutyric acid type A receptors (GABAARs) are important components of the central nervous system and they are functionally tasked with controlling neuronal excitability. These receptors are subject to post-translational modification and also to modulation by endogenous regulators, such as the neurosteroids.
Seljeset, S +3 more
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GABA signaling in the thalamus [PDF]
, 2004 Inhibition of neuronal activity in networks of the mammalian central nervous system is essential for all fundamental brain functions, ranging from perception, to consciousness, to action.
Frère, Samuel
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