Results 101 to 110 of about 16,069 (248)
iNKT cell-neutrophil crosstalk promotes colorectal cancer pathogenesis [PDF]
, 2023 Georgia Lattanzi +24 more
openalex +1 more source
Advanced Science, Volume 13, Issue 18, 27 March 2026.T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu +14 more
wiley +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu +18 more
wiley +1 more source
Kinetics and cellular site of glycolipid loading control [PDF]
, 2009 CD1d-restricted natural killer T cells (NKT cells) possess a wide range of effector and regulatory activities that are related to their ability to secrete both T helper 1 (Th1) cell- and Th2 cell-type cytokines.
Arora, Pooja +10 more
core
Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]
, 2016 Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul +2 more
core +1 more source
Advanced Science, Volume 13, Issue 14, 9 March 2026.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
eLife, 2019 Tissue homeostasis is critically dependent on the function of tissue-resident lymphocytes, including lipid-reactive invariant natural killer T (iNKT) cells.
Rebeca Jimeno +10 more
doaj +1 more source
Significance of frequencies, compositions and/or antileukemic activity of (DC-stimulated) invariant NKT, NK and CIK cells on the outcome of patients with AML, ALL and CLL [PDF]
, 2018 Invariant natural killer cells (iNKT cells), natural killer cells (NKT cells) and cytokine induced killer cells (CIK cells) and their subsets are important for immune-surveillance.
Böck, Corinna Lesley
core
Mutation of the Traj18 gene segment using TALENs to generate Natural Killer T cell deficient mice. [PDF]
, 2016 Invariant Natural Killer T (iNKT) cells are a unique subset of T lymphocytes that have been implicated in both promoting and suppressing a multitude of immune responses. In mice, iNKT cells express T cell antigen receptors (TCRs) comprising a unique TCRα
Bedel, R. +7 more
core +1 more source
European Journal of Immunology, Volume 56, Issue 3, March 2026.This is an update to the Guidelines for the Use of Flow Cytometry and Cell Sorting in Immunological Studies (Third Edition), Chapter 12C, by Cossarizza et al. A 38‐marker full‐spectrum flow cytometry panel enabling high‐resolution profiling of human γδ T cells across blood and lymphoid tissues, including robust identification of rare, tissue‐adapted ...
Mohamed Hamed +8 more
wiley +1 more source