Results 101 to 110 of about 9,712 (187)
iNKT cell regulation of B cell activation in inflammation
, 2016 The ability to combat infections through the generation of specific immune responses is critical to our survival. The immune system can react to and combat virtually any molecule presented to it, including those derived from our own body.
Thomas Hägglöf (18637204)
core
iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma.
, 2012 The T cell response to B cell lymphomas differs from the majority of solid tumors in that the malignant cells themselves are derived from B lymphocytes, key players in immune response.
Laurent Gapin +7 more
core +1 more source
Histone deacetylase 3 is required for iNKT cell development
, 2017 NKT cells are a distinct subset that have developmental requirements that often differ from conventional T cells. Here, we show that NKT-specific deletion of Hdac3 results in a severe reduction in the number of iNKT cells, particularly of NKT1 cells.
Virginia Smith Shapiro +4 more
core +1 more source
MAIT and iNKT cells in tissue homeostasis and repair
ImmunobiologyMucosal-associated invariant T (MAIT) and invariant natural killer T (iNKT) are innate-like T cells, which develop in the thymus through an original developmental program leading to the acquisition of effector memory and tissue targeting phenotypes.
Paiva, Rafael Almeida, Salou, Marion
openaire +3 more sources
Frontiers in Immunology, 2018 Invariant natural killer T (iNKT) cells are a unique T cell subset that exhibits characteristics of both innate immune cells and T cells. They express Vα14-Jα18 (Trav11-Traj18) as an invariant chain of the T cell receptor (TCR) and are restricted to the ...
Yue Ren +8 more
doaj +1 more source
Viruses, 2012 The immune system plays a major role in protecting the host against viral infection. Rapid initial protection is conveyed by innate immune cells, while adaptive immunity (including T lymphocytes) requires several days to develop, yet provides high ...
Maaike E. Ressing +4 more
doaj +1 more source
Defining iNKT Cell Subsets and Their Function by Flow Cytometry. [PDF]
Curr Protoc, 2023 Gioulbasani M, Tsagaratou A.
europepmc +1 more source
Globotriaosylceramide inhibits iNKT-cell activation in a CD1d-dependent manner
, 2016 Globotriaosylceramide (Gb3) is a glycosphingolipid present in cellular membranes that progressively accumulates in Fabry disease. Invariant Natural Killer T (iNKT) cells are a population of lipid-specific T cells that are phenotypically and functionally ...
Macedo, M. F. +9 more
core +1 more source
iNKT-cell activation by lysosphospholipids.
, 2013 During inflammation cytoplasmic, membrane and secreted phospholipases (such as PLA2) produce lysophospholipids (such as LPC) from cellular phospholipids.
Mariolina Salio (70402) +1 more
core +1 more source
Frontiers in ImmunologyInvariant natural killer T (iNKT) cells are a distinct subpopulation of innate-like T lymphocytes. They are characterized by semi-invariant T cell receptors (TCRs) that recognize both self and foreign lipid antigens presented by CD1d, a non-polymorphic ...
Guangwei Cui +4 more
doaj +1 more source