Results 21 to 30 of about 219,914 (245)

Cross-Activation of Hemichannels/Gap Junctions and Immunoglobulin-Like Domains in Innate–Adaptive Immune Responses

open access: yesFrontiers in Immunology, 2022
Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng   +8 more
doaj   +1 more source

Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells

open access: yesLife Science Alliance, 2022
Single-cell RNA sequencing of porcine ileal lymphocytes reveals similarities to human cells and discovery of porcine intestinal innate lymphoid cells. Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte function is ...
Jayne E Wiarda   +4 more
doaj   +1 more source

Close encounters of lymphoid cells and bacteria

open access: yesFrontiers in Immunology, 2016
During infections, the first reaction of the host against microbial pathogens is carried out by innate immune cells, which recognize conserved structures on pathogens, called pathogen-associated molecular patterns (PAMPs).
Aranzazu Cruz-Adalia, Esteban Veiga
doaj   +1 more source

Tissue-resident lymphocytes: sentinel of the transformed tissue

open access: yesJournal for ImmunoTherapy of Cancer, 2017
Tumor cells can be detected and cleared by lymphocytes in a process termed cancer immunosurveillance. However, the contributing cell types had not been fully characterized.
Saïda Dadi, Ming O. Li
doaj   +1 more source

Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata

open access: yeseLife, 2023
Here, we have explored the involvement of innate lymphoid cells-type 1 (ILC1) in the pathogenesis of alopecia areata (AA), because we found them to be significantly increased around lesional and non-lesional HFs of AA patients.
Rimma Laufer Britva   +5 more
doaj   +1 more source

Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection [PDF]

open access: yesViruses, 2019
Infection is restrained by the concerted activation of tissue-resident and circulating immune cells. Recent discoveries have demonstrated that tissue-resident lymphocyte subsets, comprised of innate lymphoid cells (ILCs) and unconventional T cells, have vital roles in the initiation of primary antiviral responses.
Andrew D. Hildreth   +1 more
openaire   +5 more sources

Lymphocytes: Versatile Participants in Acute Kidney Injury and Progression to Chronic Kidney Disease

open access: yesFrontiers in Physiology, 2021
Background: Acute kidney injury (AKI) remains a major global public health concern due to its high morbidity and mortality. The progression from AKI to chronic kidney disease (CKD) makes it a scientific problem to be solved.
Chujin Cao, Ying Yao, Rui Zeng
doaj   +1 more source

Tissue-Resident Lymphocytes Across Innate and Adaptive Lineages

open access: yesFrontiers in Immunology, 2018
Lymphocytes are an integral component of the immune system. Classically, all lymphocytes were thought to perpetually recirculate between secondary lymphoid organs and only traffic to non-lymphoid tissues upon activation. In recent years, a diverse family
Chun Chou, Ming O. Li
doaj   +1 more source

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

open access: yeseLife, 2016
Lymph nodes (LNs) contain innate-like lymphocytes that survey the subcapsular sinus (SCS) and associated macrophages for pathogen entry. The factors promoting this surveillance behavior have not been defined.
Yang Zhang   +9 more
doaj   +1 more source

Moving at the frontline

open access: yeseLife, 2016
The factors that regulate how immune cells called innate-like lymphocytes are localized in the tissue have been identified.
Marco Ataíde, Wolfgang Kastenmüller
doaj   +1 more source

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