Results 11 to 20 of about 287,222 (242)

What rheumatologists need to know about innate lymphocytes [PDF]

Nature Reviews Rheumatology, 2016
Many rheumatic diseases are characterized by having an autoimmune background. Determining the mechanisms underlying autoimmunity is, therefore, important to further understand these diseases and to inform future lines of research aimed at developing new ...
George C Tsokos, Kingston H G Mills, Dirk Elewaut   +2 more
exaly   +2 more sources

Cytotoxic innate intraepithelial lymphocytes control early stages of Cryptosporidium infection [PDF]

Frontiers in Immunology, 2023
BackgroundIntraepithelial lymphocytes (IELs) are the first immune cells to contact and fight intestinal pathogens such as Cryptosporidium, a widespread parasite which infects the gut epithelium. IFN-γ producing CD4+ T IELs provide an efficient and a long-
Fatima Hariss, Marie Delbeke, Karine Guyot, Pauline Zarnitzky, Mohamad Ezzedine, Gabriela Certad, Gabriela Certad, Bertrand Meresse   +7 more
doaj   +2 more sources

Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response

Journal of Advanced Research, 2023
Background: Innate and adaptive immunity are two different parts of the immune system that have different characteristics and work together to provide immune protection. Inflammasomes are a major part of the innate immune system that are expressed widely
Hongliang Zhang, Jie Gao, Yujie Tang, Tengchuan Jin, Jinhui Tao   +4 more
doaj   +2 more sources

Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level [PDF]

Nature Communications
Tissue-resident innate immune cells have important functions in both homeostasis and pathological states. Despite advances in the field, analyzing the metabolism of tissue-resident innate lymphocytes is still challenging.
Carrie Corkish, Cristhiane Favero Aguiar, David K. Finlay   +2 more
doaj   +2 more sources

Role of Innate lymphocytes in infection and inflammation

Frontiers in Immunology, 2012
Cooperation of innate and adaptive immune responses is critical for the protective immunity against various invading microbes. Distinct types of effector T cells play different roles in adaptive immune responses.
Shigeo eKoyasu, Kazuyo eMoro
doaj   +2 more sources

Editorial: Innate lymphocytes in tumor surveillance [PDF]

Frontiers in Immunology, 2022
Jörg H. Fritz, Dagmar Stoiber
doaj   +2 more sources

Decoding innate lymphoid cells and innate-like lymphocytes in asthma: pathways to mechanisms and therapies

Journal of Biomedical Science
Asthma is a chronic inflammatory lung disease driven by a complex interplay between innate and adaptive immune components. Among these, innate lymphoid cells (ILCs) and innate-like lymphocytes have emerged as crucial players in shaping the disease ...
Christina Li-Ping Thio, Jheng-Syuan Shao, Chia-Hui Luo, Ya-Jen Chang   +3 more
doaj   +2 more sources

Innate Lymphocytes in Adipose Tissue Homeostasis and Their Alterations in Obesity and Colorectal Cancer [PDF]

Frontiers in Immunology, 2018
Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of death, with burden expected to increase in the coming years.
Manuela Del Cornò, Lucia Conti, Sandra Gessani   +2 more
doaj   +2 more sources

Cardinal features of immune memory in innate lymphocytes [PDF]

Nature Immunology, 2023
Endi K Santosa, Joseph C Sun, Sun Joseph C   +2 more
exaly   +2 more sources

Atg5 Is Essential for the Development and Survival of Innate Lymphocytes. [PDF]

Cell Rep, 2016
SummaryAutophagy is an essential cellular survival mechanism that is required for adaptive lymphocyte development; however, its role in innate lymphoid cell (ILC) development remains unknown.
O'Sullivan TE, Geary CD, Weizman OE, Geiger TL, Rapp M, Dorn GW, Overholtzer M, Sun JC.   +7 more
europepmc   +2 more sources