Results 11 to 20 of about 290,827 (234)

Ontogeny of innate T lymphocytes - some innate lymphocytes are more innate then others [PDF]

open access: yesFrontiers in Immunology, 2014
Innate lymphocytes have recently received a lot of attention. However, there are different ideas about the definition of what is innate in lymphocytes. Lymphocytes without V(D)J-rearranged antigen receptors are now termed innate lymphoid cells (ILCs) and
David eVermijlen, Immo ePrinz
doaj   +4 more sources

Roles of Hepatic Innate and Innate-Like Lymphocytes in Nonalcoholic Steatohepatitis [PDF]

open access: yesFrontiers in Immunology, 2020
Nonalcoholic steatohepatitis (NASH), a progressive form of nonalcoholic fatty liver disease (NAFLD), is accompanied by steatosis, hepatocyte injury and liver inflammation, which has been a health problem in the world as one of the major high risk factors
Yongyan Chen   +3 more
doaj   +3 more sources

Fish Lymphocytes: An Evolutionary Equivalent of Mammalian Innate-Like Lymphocytes? [PDF]

open access: yesFrontiers in Immunology, 2018
Lymphocytes are the responsible of adaptive responses, as they are classically described, but evidence shows that subpopulations of mammalian lymphocytes may behave as innate-like cells, engaging non-self rapidly and without antigen presentation.
Giuseppe Scapigliati   +2 more
doaj   +5 more sources

Role of Innate lymphocytes in infection and inflammation [PDF]

open access: yesFrontiers in Immunology, 2012
Cooperation of innate and adaptive immune responses is critical for the protective immunity against various invading microbes. Distinct types of effector T cells play different roles in adaptive immune responses.
Shigeo eKoyasu, Kazuyo eMoro
doaj   +3 more sources

"Corrigendum: Ontogeny of innate T lymphocytes – some innate lymphocytes are more innate than others" [PDF]

open access: yesFrontiers in Immunology, 2015
We have found an error in our review article “Ontogeny of innate T lymphocytes – some innate lymphocytes are more innate than others.” On page 6, under the section “Mucosa-associated invariant T cells”: “In humans, this TCR consists of Vα7.2–Jα22….” Instead of “Jα22,” this should be “Jα33.” The same error is present in Table 1, under “MAIT –
David eVermijlen, Immo ePrinz
doaj   +2 more sources

Decoding innate lymphoid cells and innate-like lymphocytes in asthma: pathways to mechanisms and therapies

open access: yesJournal of Biomedical Science
Asthma is a chronic inflammatory lung disease driven by a complex interplay between innate and adaptive immune components. Among these, innate lymphoid cells (ILCs) and innate-like lymphocytes have emerged as crucial players in shaping the disease ...
Christina Li-Ping Thio   +3 more
doaj   +2 more sources

Diversity, Function and Transcriptional Regulation of Gut Innate Lymphocytes [PDF]

open access: yesFrontiers in Immunology, 2013
The innate immune system plays a critical early role in host defense against viruses, bacteria and tumour cells. Until recently, natural killer (NK) cells and lymphoid tissue inducer (LTi) cells were the primary members of the innate lymphocyte family ...
Lucille eRankin   +9 more
doaj   +10 more sources

Lineage specification in innate lymphocytes. [PDF]

open access: yesCytokine Growth Factor Rev, 2018
Innate lymphoid cells (ILCs) are immune cells that lack specific antigen receptors but possess similar effector functions as T cells. Concordantly, ILCs express many transcription factors known to be important for T cell effector function. ILCs develop from lymphoid progenitors in fetal liver and adult bone marrow.
Das A, Harly C, Yang Q, Bhandoola A.
europepmc   +5 more sources

Die Kämpfe únd schláchten—the struggles and battles of innate-like effector T lymphocytes with microbes

open access: yesFrontiers in Immunology, 2023
The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce   +3 more
doaj   +1 more source

Contributions of innate lymphocytes to allergic responses. [PDF]

open access: yesCurr Opin Allergy Clin Immunol, 2019
Purpose of reviewAllergic diseases represent a growing global health concern, especially among pediatric populations. Current strategies for the treatment of allergies and asthma focus on limiting the severity of the symptoms; however, additional research investigating the mechanisms promoting inflammation in the context of allergic reactions may lead ...
Inclan-Rico JM, Ponessa JJ, Siracusa MC.
europepmc   +4 more sources

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