Results 31 to 40 of about 290,827 (234)
Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells. [PDF]
PLoS ONE, 2015 Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers.
Kanako Shimizu +8 more
doaj +1 more source
Tissue-Resident Cytolytic Innate Lymphocytes in Cancer. [PDF]
J Immunol, 2018 Abstract Innate lymphoid cells (ILCs) are critical components of tissues in the body, providing a first line of defense against challenges to host integrity. In contrast to strictly cytokine-producing helper ILCs, resident innate lymphocyte populations with cytolytic potential have been identified in multiple tissues in both mouse and ...
Nixon BG, Li MO.
europepmc +4 more sources
Innate Lymphocytes and Malaria – Players or Spectators?
Trends in Parasitology, 2019 Malaria remains an important global disease. Despite significant advances over the past decade in reducing disease morbidity and mortality, new measures are needed if malaria is to be eliminated. Significant advances in our understanding about host immune responses during malaria have been made, opening up opportunities to generate long-lasting ...
Ng, Susanna S, Engwerda, Christian R
openaire +5 more sources
Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells
Life Science Alliance, 2022 Single-cell RNA sequencing of porcine ileal lymphocytes reveals similarities to human cells and discovery of porcine intestinal innate lymphoid cells. Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte function is ...
Jayne E Wiarda +4 more
doaj +1 more source
Close encounters of lymphoid cells and bacteria
Frontiers in Immunology, 2016 During infections, the first reaction of the host against microbial pathogens is carried out by innate immune cells, which recognize conserved structures on pathogens, called pathogen-associated molecular patterns (PAMPs).
Aranzazu Cruz-Adalia, Esteban Veiga
doaj +1 more source
Lymphocytes: Versatile Participants in Acute Kidney Injury and Progression to Chronic Kidney Disease
Frontiers in Physiology, 2021 Background: Acute kidney injury (AKI) remains a major global public health concern due to its high morbidity and mortality. The progression from AKI to chronic kidney disease (CKD) makes it a scientific problem to be solved.
Chujin Cao, Ying Yao, Rui Zeng
doaj +1 more source
Tissue-resident lymphocytes: sentinel of the transformed tissue
Journal for ImmunoTherapy of Cancer, 2017 Tumor cells can be detected and cleared by lymphocytes in a process termed cancer immunosurveillance. However, the contributing cell types had not been fully characterized.
Saïda Dadi, Ming O. Li
doaj +1 more source
Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection [PDF]
Viruses, 2019 Infection is restrained by the concerted activation of tissue-resident and circulating immune cells. Recent discoveries have demonstrated that tissue-resident lymphocyte subsets, comprised of innate lymphoid cells (ILCs) and unconventional T cells, have vital roles in the initiation of primary antiviral responses.
Andrew D. Hildreth +1 more
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Selective cytotoxicity and anticancer activity: ROS-induced cell death facilitated by metal complex [PDF]
BIO Web of ConferencesHepatocellular carcinoma (HCC) recurrence rate consists of 10%-20% and remains the leading cause of cancer-related death. We have successfully designed the protocol for adoptive immunotherapy to liver cirrhotic patients with HCC.
Sato Hitoshi +4 more
doaj +1 more source
Group 2 innate lymphocytes at the interface between innate and adaptive immunity [PDF]
Annals of the New York Academy of Sciences, 2018 AbstractGroup 2 innate lymphoid cells (ILC2) are innate immune cells that respond rapidly to their environment through soluble inflammatory mediators and cell‐to‐cell interactions. As tissue‐resident sentinels, ILC2 help orchestrate localized type 2 immune responses.
Martijn J, Schuijs, Timotheus Y F, Halim
openaire +2 more sources