Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection [PDF]
Cell Host and Microbe, 2018 Nydiaris Hernández-Santos +2 more
exaly +2 more sources
Roles of Hepatic Innate and Innate-Like Lymphocytes in Nonalcoholic Steatohepatitis
Frontiers in Immunology, 2020 Nonalcoholic steatohepatitis (NASH), a progressive form of nonalcoholic fatty liver disease (NAFLD), is accompanied by steatosis, hepatocyte injury and liver inflammation, which has been a health problem in the world as one of the major high risk factors
Yongyan Chen +3 more
doaj +1 more source
Ontogeny of innate T lymphocytes - some innate lymphocytes are more innate then others
Frontiers in Immunology, 2014 Innate lymphocytes have recently received a lot of attention. However, there are different ideas about the definition of what is innate in lymphocytes. Lymphocytes without V(D)J-rearranged antigen receptors are now termed innate lymphoid cells (ILCs) and
David eVermijlen, Immo ePrinz
doaj +1 more source
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]
, 2013 Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M +5 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2022 Cancer immunotherapy has led to impressive advances in cancer treatment. Unfortunately, in a high percentage of patients is difficult to consistently restore immune responses to eradicate established tumors. It is well accepted that adaptive immune cells,
Rosalia Busà +8 more
doaj +1 more source
The cGAS-STING Pathway: A Promising Immunotherapy Target
Frontiers in Immunology, 2021 With the continuous development of immunotherapy, researchers have paid more attention to the specific immune regulatory mechanisms of various immune responses in different diseases.
Liang Ou +3 more
doaj +1 more source
Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells
Life Science Alliance, 2022 Single-cell RNA sequencing of porcine ileal lymphocytes reveals similarities to human cells and discovery of porcine intestinal innate lymphoid cells. Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte function is ...
Jayne E Wiarda +4 more
doaj +1 more source
Overview of the development, characterization, and function of human types 1, 2, and 3 innate lymphoid cells [PDF]
Einstein (São Paulo)Hematopoiesis is characterized by the differentiation and maturation of multipotent stem cells into hematopoietic cells. Common lymphoid progenitor cells differentiate into B and T lymphocytes; natural killer cells can also originate from common lymphoid
Laiz Cameirão Bento +2 more
doaj +1 more source
Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation. [PDF]
PLoS ONE, 2014 Interleukin (IL)-4 is a cytokine classically associated with CD4(+) T helper type 2 differentiation, but has been recently shown to also be required for the development of CD8(+) innate-like lymphocytes.
Shannon A Carty +2 more
doaj +1 more source
Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells. [PDF]
PLoS ONE, 2015 Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers.
Kanako Shimizu +8 more
doaj +1 more source