Results 1 to 10 of about 191,579 (251)
HiJAKing innate lymphoid cells? [PDF]
Frontiers in Immunology, 2017 The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells.
Gadina, Massimo +2 more
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Epigenomic Views of Innate Lymphoid Cells [PDF]
Frontiers in Immunology, 2017 The discovery of innate lymphoid cells (ILCs) with selective production of cytokines typically attributed to subsets of T helper cells forces immunologists to reassess the mechanisms by which selective effector functions arise.
Giuseppe Sciumè +3 more
doaj +3 more sources
Characteristic of innate lymphoid cells (ILC)
Postępy Higieny i Medycyny Doświadczalnej, 2014 Innate lymphoid cells (ILC) is a newly described family of immune cells that are part of the natural immunity which is important not only during infections caused by microorganisms, but also in the formation of lymphoid tissue, tissue remodeling after damage due to injury and homeostasis tissue stromal cells.
Mateusz Adamiak +2 more
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Innate Lymphoid Cells in Intestinal Inflammation [PDF]
Frontiers in Immunology, 2017 Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn’s disease (CD) and ulcerative colitis.
Alessandra Geremia +1 more
doaj +4 more sources
Innate lymphoid cells in neuroinflammation
Frontiers in Cellular NeuroscienceInnate lymphoid cells (ILCs) are largely tissue-resident cells that participate in the maintenance of tissue homeostasis and react early to inflammatory events.
Daria Kveštak +4 more
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Why Innate Lymphoid Cells? [PDF]
Immunity, 2018 Innate lymphoid cells (ILCs) are positioned in tissues perinatally, constitutively express receptors responsive to their organ microenvironments, and perform an arsenal of effector functions that overlap those of adaptive CD4+ T cells. Based on knowledge regarding subsets of invariant-like lymphocytes (e.g., natural killer T [NKT] cells, γδ T cells ...
Maya E. Kotas, Richard M. Locksley
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Human innate lymphoid cells [PDF]
Journal of Allergy and Clinical Immunology, 2016 Innate lymphoid cells (ILCs) are increasingly acknowledged as important mediators of immune homeostasis and pathology. ILCs act as early orchestrators of immunity, responding to epithelium-derived signals by expressing an array of cytokines and cell-surface receptors, which shape subsequent immune responses.
Jenny Mjösberg, Hergen Spits
openaire +7 more sources
Innate lymphoid cells and infectious diseases
Innate ImmunityInnate lymphoid cells (ILCs) are the main resident lymphocytes that mostly reside in tissues owing to the lack of adaptive antigen receptors. These cells are involved in early anti-infective immunity, antitumour immunity, regulation of tissue ...
Ting Yuan +5 more
doaj +3 more sources
Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells
Frontiers in Immunology, 2023 NK cells represent important effectors that play a major role in innate defences against pathogens and display potent cytolytic activity against tumor cells. An array of surface receptors finely regulate their function and inhibitory checkpoints, such as
Francesca Romana Mariotti +6 more
doaj +1 more source
Molecular Cancer, 2023 Autophagy is an essential cellular homeostasis pathway initiated by multiple stimuli ranging from nutrient deprivation to viral infection, playing a key role in human health and disease.
Manuela Giansanti +7 more
doaj +1 more source