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Innate Lymphoid Cells in Tumor Immunity [PDF]
Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue inducer (LTi) cells and the recently identified ILC1s, ILC2s and ILC3s.
Jasper van Beek +3 more
core +3 more sources
Innate Lymphoid Cells in Intestinal Inflammation [PDF]
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn’s disease (CD) and ulcerative colitis.
Alessandra Geremia +1 more
doaj +4 more sources
Innate Lymphoid Cells in Crohn’s Disease [PDF]
Innate lymphoid cells (ILCs) are a large family of cells of the immune system that performs various functions in immune defense, inflammation, and tissue remodeling. As a part of the innate immune system, ILCs are a distinct form of lymphocytes different
Ying Wu, Jun Shen
doaj +3 more sources
Innate lymphoid cells in the airways [PDF]
The airways, similar to other mucosal surfaces, are continuously exposed to the outside environment and a barrage of antigens, allergens, and microorganisms. Of critical importance therefore is the ability to mount rapid and effective immune responses to control commensal and pathogenic microbes, while simultaneously limiting the extent of these ...
Jennifer A, Walker, Andrew, McKenzie
openaire +2 more sources
Innate lymphoid cells and the skin [PDF]
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367-1371, 2010, Nat Rev Immunol 13: 145-149, 2013).
Salimi, Maryam, Ogg, Graham
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Natural killer cells and type 1 innate lymphoid cells in cancer
International audienceInnate lymphoid cells (ILCs) are a group of innate lymphocytes that do not express RAG-dependent rearranged antigen-specific cell surface receptors.
Vivier, Eric +5 more
core +1 more source
Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response [PDF]
International audienceNatural killer (NK) cells are known to be able to kill established tumor cell lines, but important caveats remain regarding their roles in the detection and elimination of developing primary tumors.
Justine Galluso +17 more
core +1 more source
The evolution of innate lymphoid cells [PDF]
Innate lymphoid cells (ILCs) are the most recently discovered group of immune cells. Understanding their biology poses many challenges. We discuss here the current knowledge on the appearance of ILC subsets during evolution and propose how the connection between ILCs and T cells contributes to the robustness of immunity and hence to the fitness of the ...
Vivier, Eric +3 more
openaire +6 more sources
Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]
Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid +15 more
core +1 more source
Innate Lymphoid Cells (ILC) are tissue-resident effector lymphocytes that differ from the B and T lymphocytes subsets since they lack specific antigen receptors derived from gene rearrangements. They can be divided into two groups, cytotoxic ILC (NK cells) which are dependent on the transcription factors Eomes and T-bet and produce IFN-γ, and helper ...
Crinier, Adeline +3 more
openaire +3 more sources

