Results 21 to 30 of about 191,579 (251)
Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]
, 2019 Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM +9 more
core +4 more sources
Innate lymphoid cells and cancer
Nature Immunology, 2022 The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and ILC3, which participate in immune responses to virus, bacteria, parasites and transformed cells. ILC1, ILC2 and ILC3 subsets are mostly tissue-resident, and are profoundly imprinted by their organ of residence.
Jacquelot, Nicolas +3 more
openaire +3 more sources
Enrichment of innate lymphoid cell populations in gingival tissue [PDF]
, 2018 Innate lymphoid cells (ILCs) are a population of lymphocytes that act as the first line of immunologic defense at mucosal surfaces. The ILC family in the skin, lungs, and gastrointestinal tissues has been investigated, and there are reports of individual
Adrados Planell, A. +5 more
core +2 more sources
IL-15 sustains IL-7R-independent ILC2 and ILC3 development [PDF]
, 2017 The signals that maintain tissue-resident innate lymphoid cells (ILC) in different microenvironments are incompletely understood. Here we show that IL-7 receptor (IL-7R) is not strictly required for the development of any ILC subset, as residual cells ...
Bando, Jennifer K +5 more
core +2 more sources
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013 Innate lymphoid cells (ILCs) represent a novel family of developmentally related hematopoietic effectors with central roles in innate immune responses to infections, lymphoid organogenesis, intestinal homeostasis, and wound healing.1 The prototypes of the ILC family are natural killer cells and lymphoid tissue–inducer cells.
Alain, Tedgui, Hafid, Ait-Oufella
openaire +2 more sources
Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]
, 2013 Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A +2 more
core +2 more sources
Frontiers in Immunology, 2020 The transcription factor TCF-1 (encoded by Tcf7) plays critical roles in several lineages of hematopoietic cells. In this study, we examined the molecular basis for Tcf7 regulation in T cells, innate lymphoid cells, and migratory conventional dendritic ...
Christelle Harly +9 more
doaj +1 more source
Innate Lymphoid Cells in Autoimmune Diseases
Frontiers in Immunology, 2022 Innate lymphoid cells (ILC) are a heterogeneous group of immune cells characterized by lymphoid morphology and cytokine profile similar to T cells but which do not express clonally distributed diverse antigen receptors.
Aurelie S. Clottu +4 more
doaj +1 more source
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]
, 2016 Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank +5 more
core +1 more source
Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]
, 2015 Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A +9 more
core +2 more sources