Results 11 to 20 of about 2,229,414 (244)
Resident memory macrophages and trained innate immunity at barrier tissues [PDF]
eLifeInnate immune memory, or trained innate immunity (TII), represents a form of immunological adaptation in which innate immune cells, including myeloid and lymphoid cells, retain a trained state following prior exposure to immunological stimuli.
Alisha Kang +4 more
doaj +2 more sources
Adv Immunol, 2015 Memory T cells are usually considered to be a feature of a successful immune response against a foreign antigen, and such cells can mediate potent immunity.
Jameson SC, Lee YJ, Hogquist KA.
europepmc +2 more sources
In Vivo Zymosan Treatment Induces IL15-Secreting Macrophages and KLRG1-Expressing NK Cells in Mice
Molecules, 2023 Beta-glucan (β-glucan) is a natural polysaccharide produced by fungi, bacteria, and plants. Although it has been reported that β-glucan enhances innate immune memory responses, it is unclear whether different types of β-glucans display similar immune ...
Hyun Jung Park +7 more
doaj +1 more source
eLife, 2021 Immunity to malaria is often considered slow to develop but this only applies to defense mechanisms that function to eliminate parasites (resistance).
Wiebke Nahrendorf +2 more
doaj +1 more source
Frontiers in Immunology, 2021 The induction of trained immunity represents an emerging concept defined as the ability of innate immune cells to acquire a memory phenotype, which is a typical hallmark of the adaptive response.
Orlando A. Acevedo +5 more
doaj +1 more source
Innate Immunomodulation in Food Animals: Evidence for Trained Immunity?
Frontiers in Immunology, 2020 Antimicrobial resistance (AMR) is a significant problem in health care, animal health, and food safety. To limit AMR, there is a need for alternatives to antibiotics to enhance disease resistance and support judicious antibiotic usage in animals and ...
Kristen A. Byrne +2 more
doaj +1 more source
hUCMSCs Mitigate LPS-Induced Trained Immunity in Ischemic Stroke
Frontiers in Immunology, 2020 Innate immune memory is a part of the innate immune system that facilitates the elimination of pathogens. However, it may exacerbate neuropathology. In this study, we found that innate immune memory is detrimental in stroke, because it promotes the acute
Yi-wei Feng +17 more
doaj +1 more source
Personalised Profiling of Innate Immune Memory Induced by Nano-Imaging Particles in Human Monocytes
Frontiers in Immunology, 2021 Engineered nanoparticles used for medical purposes must meet stringent safety criteria, which include immunosafety, i.e., the inability to activate possibly detrimental immune/inflammatory effects.
Giacomo Della Camera +13 more
doaj +1 more source
Synthesis and validation of click-modified of NOD1/2 agonists [preprint] [PDF]
, 2023 This article is a preprint. Preprints are preliminary reports of work that have not been certified by peer review.NOD1 and NOD2 sense small bacterial peptidoglycan fragments often called muropeptides.
Silverman, Neal +7 more
core +1 more source
Genetic dissection of innate immune memory in Drosophila melanogaster
Frontiers in Immunology, 2022 Current studies have demonstrated that innate immunity possesses memory characteristics. Although the molecular mechanisms underlying innate immune memory have been addressed by numerous studies, genetic variations in innate immune memory and the ...
Chang Tang +2 more
doaj +1 more source