Results 21 to 30 of about 2,229,414 (244)

Innate Immune Memory Responses in Organ Transplantation. [PDF]

Arterioscler Thromb Vasc Biol
Innate immunity is a critical contributor to graft rejection and cardiovascular complications after organ transplantation, with increasing evidence indicating that innate immune memory significantly influences ...
de Jong LC, Rother N, Duivenvoorden R.
europepmc   +2 more sources

Induction of Innate Immune Memory by Engineered Nanoparticles in Monocytes/Macrophages: From Hypothesis to Reality

Frontiers in Immunology, 2020
The capacity of engineered nanoparticles to activate cells of the innate immune system, in particular monocytes and macrophages, is considered at the basis of their toxic/inflammatory effects.
Paola Italiani, Giacomo Della Camera, Diana Boraschi   +2 more
doaj   +1 more source

Different Regulation of Interleukin-1 Production and Activity in Monocytes and Macrophages: Innate Memory as an Endogenous Mechanism of IL-1 Inhibition

Frontiers in Pharmacology, 2017
Production and activity of interleukin (IL)-1β are kept under strict control in our body, because of its powerful inflammation-promoting capacity. Control of IL-1β production and activity allows IL-1 to exert its defensive activities without causing ...
Mariusz P. Madej, Elfi Töpfer, Diana Boraschi, Paola Italiani   +3 more
doaj   +1 more source

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J.   +34 more
core   +1 more source

Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]

, 2013
Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M, Cerutti, A, Andrea Cerutti, Puga, I, Montserrat Cols, Irene Puga   +5 more
core   +1 more source

Innate immunity against HIV: a priority target for HIV prevention research. [PDF]

, 2010
This review summarizes recent advances and current gaps in understanding of innate immunity to human immunodeficiency virus (HIV) infection, and identifies key scientific priorities to enable application of this knowledge to the development of novel ...
PAXTON W, ROMARIS M, LINDBLAD E, DONCEL G, BORROW P, Persephone Borrow, Borrow, P, LEHNER T, DE MAGISTRIS MT, Shattock, Robin J., MEDAGLINI, DONATA, Vyakarnam, Annapurna, PATTERSON S, Annapurna Vyakarnam, POLI G, EUROPRISE WORKING GROUP BOGERS W, KIRCHHOFF F, KELLY C, TOWERS G, SILVESTRI G, DEBRE P, Robin J Shattock, Shattock, RJ, SHATTOCK RJ, Vyakarnam Annapurna, Borrow, Persephone, Borrow Persephone, GOODIER M, null null, SPECK R, EUROPRISE Working Group, GEIJTENBEEK T, Vyakarnam, A, Shattock Robin J, WAGNER H., VYAKARNAM A   +35 more
core   +1 more source

Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. [PDF]

PLoS Pathogens, 2011
While immunological memory has long been considered the province of T- and B-lymphocytes, it has recently been reported that innate cell populations are capable of mediating memory responses. We now show that an innate memory immune response is generated
Geoffrey O Gillard, Maytal Bivas-Benita, Avi-Hai Hovav, Lauren E Grandpre, Michael W Panas, Michael S Seaman, Barton F Haynes, Norman L Letvin   +7 more
doaj   +1 more source

Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation

, 2020
There is increasing evidence that suggest the presence of innate immune memory as reflected in the altered responses from programmed innate leukocyte challenged with varying natures and signal strength of inflammatory challenges. The rudimentary “memory”

core   +1 more source

Chitin modulates innate immune responses of keratinocytes. [PDF]

, 2011
Chitin, after cellulose the second most abundant polysaccharide in nature, is an essential component of exoskeletons of crabs, shrimps and insects and protects these organisms from harsh conditions in their environment.
Korting, Hans Christian, Koller, Barbara, Thomas Ruzicka, Korting Hans Christian, Rupec Rudolph, Müller-Wiefel Alisa Sophie, Alisa Sophie Müller-Wiefel, Müller-Wiefel, Alisa Sophie, Rudolph Rupec, Koller Barbara, Hans Christian Korting, Ruzicka, Thomas, Barbara Koller, Ruzicka Thomas, Rupec, Rudolph   +14 more
core   +2 more sources

Innate immune memory in fibroblasts [PDF]

, 2018
The innate immune system is a generic response to infection or injury. Evidence shows the innate response has immunological memory capable of altering subsequent responses to stimuli.
Crowley, Thomas
core   +6 more sources