Results 51 to 60 of about 1,266 (160)

In silico analyses suggest the cardiac ganglion of the lobster, Homarus americanus, contains a diverse array of putative innexin/innexin-like proteins, including both known and novel members of this protein family [PDF]

open access: yes, 2020
Gap junctions are physical channels that connect adjacent cells, permitting the flow of small molecules/ions between the cytoplasms of the coupled units.
Hull, J. Joe   +2 more
core  

Gap junctions: historical discoveries and new findings in the Caenorhabditis elegans nervous system

open access: yesBiology Open, 2020
Gap junctions are evolutionarily conserved structures at close membrane contacts between two cells. In the nervous system, they mediate rapid, often bi-directional, transmission of signals through channels called innexins in invertebrates and connexins ...
Eugene Jennifer Jin   +3 more
doaj   +1 more source

Mechanisms Underlying the Initiation and Termination of Collective Cell Migration: Perspectives for Understanding Development and Cancer Metastasis

open access: yesBioEssays, Volume 48, Issue 4, April 2026.
How collective cell migration starts and stops is a fundamental question but remains poorly understood. This review discusses the distinct mechanisms in in vivo models and cancer metastasis that define the regulatory pathways and collective features governing the initiation and termination of collective cell migration.
Guangxia Miao
wiley   +1 more source

A Gap Junction Protein, Inx2, Modulates Calcium Flux to Specify Border Cell Fate during Drosophila oogenesis. [PDF]

open access: yesPLoS Genetics, 2017
Intercellular communication mediated by gap junction (GJ) proteins is indispensable during embryogenesis, tissue regeneration and wound healing. Here we report functional analysis of a gap junction protein, Innexin 2 (Inx2), in cell type specification ...
Aresh Sahu   +3 more
doaj   +1 more source

The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic muscle contraction in C. elegans

open access: yesNature Communications, 2023
FMRFamides are evolutionarily conserved neuropeptides that play critical roles in behavior, energy balance, and reproduction. Here, we show that FMRFamide signaling from the nervous system is critical for the rhythmic activation of a single cell of ...
Ukjin Choi   +3 more
doaj   +1 more source

Cloning and Expression of Hydra Innexin 2, a Gap Junction Protein Required for Coordinated Contraction of the Body Column [PDF]

open access: yes, 2020
In invertebrates gap junctions are formed by the innexin family of proteins. Remarkably, the genome of Hydra magnipapillata contains 17 innexin genes. This study focused on Hydra innexin-2 (h-Inx2) which is expressed in nerve cells and plays a role in ...
O\u27Brien, Ashley
core  

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Innexins: Expression, Regulation, and Functions

open access: yesFrontiers in Physiology, 2018
The innexin (Inx) proteins form gap junction channels and non-junctional channels (named hemichannels) in invertebrates. These channels participate in cellular communication playing a relevant role in several physiological processes.
Juan Güiza   +4 more
doaj   +1 more source

De Novo Transcriptome Assembly Reveals Insights Into Osmoregulation and Oxidative Stress Response in the Gills of the Southern King Crab (Lithodes santolla)

open access: yesEcology and Evolution, Volume 15, Issue 11, November 2025.
The Southern King Crab (Lithodes santolla), an ecologically and commercially important species in sub‐Antarctic waters. In this study, we assembled the first gill de novo transcriptome of L. santolla to characterize gene expression related to environmental responses.
Alexandra Brante   +5 more
wiley   +1 more source

An Innexin-Dependent Cell Network Establishes Left-Right Neuronal Asymmetry in C. elegans [PDF]

open access: yes, 2007
SummaryGap junctions are widespread in immature neuronal circuits, but their functional significance is poorly understood. We show here that a transient network formed by the innexin gap-junction protein NSY-5 coordinates left-right asymmetry in the ...
VanHoven, Miri K.   +4 more
core   +1 more source

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