Results 71 to 80 of about 1,266 (160)
Biomolecules, 2020 In Caenorhabditis elegans, gap junctions couple cells of the somatic gonad with the germline to support germ cell proliferation and gametogenesis. A strong loss-of-function mutation (T239I) affects the second extracellular loop (EL2) of the somatic INX-8
Todd Starich, David Greenstein
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A Single‐Cell Atlas of Crab Ovary Provides New Insights Into Oogenesis in Crustaceans
Advanced Science, Volume 12, Issue 2, January 13, 2025.Crabs are a valuable resource for aquatic ecosystems worldwide. This study presents a high‐resolution single‐cell atlas to study the oogenesis process in crabs. The results indicate the conserved trajectory of oogenesis from oogonia to oocytes. Moreover, based on the distribution features and subsequent functional analysis, the study determined several
Li Lu, Tao Wang, An Liu, Haihui Ye
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Are there gap junctions without connexins or pannexins?
BMC Evolutionary Biology, 2019 Background Gap junctions (GJ) are one of the most common forms of intercellular communication. GJs are assembled from proteins that form channels connecting the cytoplasm of adjacent cells.
Georgy A. Slivko-Koltchik +2 more
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Pharmacological and Genetic Evidence for Gap Junctions as Potential New Insecticide Targets in the Yellow Fever Mosquito, Aedes aegypti. [PDF]
PLoS ONE, 2015 The yellow fever mosquito Aedes aegypti is an important vector of viral diseases that impact global health. Insecticides are typically used to manage mosquito populations, but the evolution of insecticide resistance is limiting their effectiveness. Thus,
Travis L Calkins, Peter M Piermarini
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Evolutionary origin of the nervous system from Ctenophora prospective
Evolution &Development, Volume 26, Issue 4, July 2024.This review discusses the evolutionary origin of the nervous system in light of the latest findings in the neuroscience of Ctenophora, one of the most enigmatic and earliest diverging animal lineages. Abstract Nervous system is one of the key adaptations underlying the evolutionary success of the majority of animal groups. Ctenophores (or comb jellies)
Maria Y. Sachkova
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, 2022 Large-pore channels, including those formed by connexin, pannexin, innexin proteins, are part of a broad family of plasma membrane channels found in vertebrates and invertebrates, which share topology features.
García, Aníbal +23 more
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What can insects teach us about hearing loss?
The Journal of Physiology, Volume 602, Issue 2, Page 297-316, 15 January 2024.Abstract figure legend Schematic of insect and mammalian auditory systems with homologous cell types colour matched. Common causes of hearing loss and shared mechanisms are depicted in the centre. Shared mechanisms of genetic disorders include cytoskeletal and ion channel disorders.
Ben Warren, Daniel Eberl
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Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that ...
Karina eSimonsen +3 more
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, 2003 Innexins are a family of membrane proteins involved in the formation of gap junctions in invertebrates. They have been found to participate in several aspects of cell differentiation and in embryonic patterning through the formation of specific ...
GERACI, GIUSEPPE +12 more
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Reverse genetic screening of innexin gap junction proteins in drosophila neurons [PDF]
, 2016 The reflexive response and perception of pain (nociception) is an evolutionarily conserved process in animals. Pain can be a major health concern and current treatments often prove insufficient, especially in regards to chronic pain.
Fox, Shannon P.
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