Results 61 to 70 of about 1,266 (160)
, 2002 A novel member of the innexin family (cvinx) has been isolated from the annelid polychaete worm ChaetopterusvariopedatususingaPCRapproachongenomic DNA and sequence analysis on genomic DNA clones. The gene is present in aHindIII-HindIII segment of 2250 bp
POTENZA N. +7 more
core +2 more sources
, 2020 We recently demonstrated that heteromerization of innexins 2 and 3 from Drosophila melanogaster (Dm) is crucial for epithelial organization and polarity of the embryonic epidermis.
Corinna Lehmann +5 more
core
The Journal of Physiology, Volume 603, Issue 15, Page 4255-4291, 1 August 2025.Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich +9 more
wiley +1 more source
Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
Biology, 2022 For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
doaj +1 more source
Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity
The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez +3 more
wiley +1 more source
The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C. elegans. [PDF]
PLoS Genetics, 2012 The Caenorhabditis elegans left and right AWC olfactory neurons communicate to establish stochastic asymmetric identities, AWC(ON) and AWC(OFF), by inhibiting a calcium-mediated signaling pathway in the future AWC(ON) cell. NSY-4/claudin-like protein and
Yi-Wen Hsieh +2 more
doaj +1 more source
Recent advances in structural characterization of volume‐regulated anion channels (VRACs)
The Journal of Physiology, Volume 603, Issue 15, Page 4201-4211, 1 August 2025.Abstract figure legend Native LRRC8 channels are obligatory heteromers comprising LRRC8A and at least one other paralogue (LRRC8B‐E) with an unknown stoichiometry. LRRC8A and LRRC8D homomers form non‐functional hexameric channels or hexameric channels with abnormal functional properties.
Erkan Karakas +2 more
wiley +1 more source
MedComm, Volume 6, Issue 5, May 2025.Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes +4 more
wiley +1 more source
Effect of eGFP (black squares) and innexin (red circles) dsRNA injection on mosquito survival.
, 2015 Values are means ± SEM. n = 3 replicates of 24 mosquitoes. Asterisks indicate a significant difference in survival between eGFP and innexin dsRNA injected mosquitoes as determined by a two-way ANOVA with a Holm-Sidak’s post-hoc test.
Travis L. Calkins (790732) +1 more
core +1 more source
Tryptophan Scanning Mutagenesis of the First Transmembrane Domain of the Innexin Shaking-B(Lethal) [PDF]
, 2011 The channel proteins of gap junctions are encoded by two distinct gene families, connexins, which are exclusive to chordates, and innexins/pannexins, which are found throughout the animal kingdom.
I. Martha Skerrett +6 more
core +1 more source