Results 141 to 150 of about 582,708 (219)

Sensory neuron inositol 1,4,5-trisphosphate receptors contribute to chronic mechanoreflex sensitization in rats with simulated peripheral artery disease.

Am J Physiol Regul Integr Comp Physiol, 2021
Rollins KS, Butenas ALE, Williams AC, Copp SW.   +3 more
europepmc   +1 more source

Cryo-EM insights into isoform-specific properties of the IP3R2 channel

Nature Communications
Calcium release through inositol 1,4,5-trisphosphate receptors (IP3Rs) is a fundamental signaling mechanism that regulates diverse cellular processes.
Mariah R. Baker, Xiaoxuan Lin, Guizhen Fan, Ariel Martinez-Chavez, Larry E. Wagner, Sundeep Malik, Tyler Allison, Briar Bell, Alexander B. Seryshev, Julio Cordero-Morales, Matthew L. Baker, David I. Yule, Irina I. Serysheva   +12 more
doaj   +1 more source

d-<i>chiro</i>-Inositol Ribophostin: A Highly Potent Agonist of d-<i>myo</i>-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities. [PDF]

J Med Chem, 2020
Mills SJ, Rossi AM, Konieczny V, Bakowski D, Taylor CW, Potter BVL.   +5 more
europepmc   +1 more source

Synthesis of myo-Inositol-1,4,5-trisphosphate and myo-Inositol-1,4-bisphosphate

, 1992
Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a second messenger mobilizing Ca2+ and its physiological metabolite in the intracellular signal transduction pathway, were synthesized from myo-inositol ...
Moon, Sung-Hwan, Chung, Sung Kee, CHANG, YOUNG TAE, Ryu, Youngha   +3 more
core  

Soluble and particulate inositol 1,4,5-trisphosphate 5-phosphatases show common antigenic determinants.

, 1990
Inositol 1,4,5-trisphosphate 5-phosphatase catalyses the dephosphorylation of the phosphate in the 5-position from inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate.
Verjans, Benoît, Hollande, F, Lejeune, C, Moreau, Colette, Erneux, Christophe   +4 more
core  

Synthesis of myo-Inositol-1,4,5-2,4,6-and 1,3,5-trisphosphate

, 1994
myo-Inosiol-1,4,5-trisphosphate(1) is well established as a second messenger mobilizing Ca2+ in the intracellular signal transduction pathway. Compound 1 and its positional isomers, myo-Inositol 2,4,6-trisphosphate(2) and -1,3,5-trisphosphate(3) were ...
Chung, Sung-Kee, CHANG, YOUNG TAE, Sohn, Kwang-Hoon   +2 more
core  

Phosphorylation of the Inositol 1,4,5-Trisphosphate Receptor [PDF]

Journal of Biological Chemistry, 1996
Padmini Komalavilas, Thomas M. Lincoln
openaire   +1 more source

Inositol 1,4,5-trisphosphate receptors and their protein partners as signalling hubs. [PDF]

J Physiol, 2016
Prole DL, Taylor CW.
europepmc   +1 more source

Dual regulation of inositol 1,4,5-trisphosphate receptors by inositol 1,4,5-trisphosphate and phosphatidylinositol 4,5-bisphosphate

Ca2+ is a universal and effective intracellular messenger, which holds a central role in the regulation of a vast array of cellular processes. Inositol 1,4,5-trisphosphate receptors (IP3Rs) are key signal integrators, which transform extracellular stimuli into intracellular Ca2+ signals. Only immobilised IP3Rs, licensed by association with KRas-induced
openaire   +1 more source

Inositol 1,4,5-Trisphosphate Receptor Down-regulation Is Activated Directly by Inositol 1,4,5-Trisphosphate Binding [PDF]

Journal of Biological Chemistry, 1999
Chang-Cheng Zhu, Teiichi Furuichi, Katsuhiko Mikoshiba, Richard J.H. Wojcikiewicz   +3 more
openaire   +1 more source