Results 131 to 140 of about 582,708 (219)

Phosphatidylethanol affects inositol 1,4,5-trisphosphate levels in NG108-15 neuroblastoma x glioma hybrid cells

, 1993
Phosphatidylethanol is formed by phospholipase D in animal cells exposed to ethanol. Previous reports have demonstrated that the degradation of phosphatidylethanol is slow, indicating that this lipid may be present in the cells after ethanol itself has ...
Alling, Christer, Gustavsson, L, Rodriguez, F D, Lundqvist, C, Simonsson, Per   +4 more
core   +2 more sources

Modulation of cytosolic calcium signaling by protein kinase A-mediated phosphorylation of inositol 1,4,5-trisphosphate receptors

Biological Research, 2004
Calcium release via intracellular Ca2+ release channels is a central event underpinning the generation of numerous, often divergent physiological processes.
STEPHEN V STRAUB, LARRY E WAGNER II, JASON I.E BRUCE, DAVID I YULE   +3 more
doaj  

Abnormal spatial diffusion of Ca²⁺ in F508del-CFTR airway epithelial cells

Respiratory Research, 2008
Background In airway epithelial cells, calcium mobilization can be elicited by selective autocrine and/or paracrine activation of apical or basolateral membrane heterotrimeric G protein-coupled receptors linked to phospholipase C (PLC) stimulation, which
Becq Frédéric, Cantereau Anne, Norez Caroline, Antigny Fabrice, Vandebrouck Clarisse   +4 more
doaj   +1 more source

Patterns of Acute Liver Injury and Post‐Acute Liver Sequelae of COVID‐19

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is known to cause acute liver injury (ALI) in COVID‐19 patients. This study explores the association between ALI patterns and the occurrence of long‐term hepatic complications in patients with and without existing chronic liver disease (CLD).
Basile Njei, Janet Tate, Vincent Lo Re III, Joseph T. King Jr, Joseph K. Lim, Tamar Taddei, Amy C. Justice   +6 more
wiley   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao, Yuanyan Liu   +10 more
wiley   +1 more source

Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]

, 2006
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V, Panchin, YV, Vanden Abeele, F, Fabien Vanden Abeele, Panchin, Yuri V, Gordienko, D, Yuri V. Panchin, Baranova, AV, Skryma, R, Baranova, Ancha, V, Skryma, Roman, Gordienko, Dmitri, Gabriel Bidaux, Beck, Benjamin, Ivanov, DV, Prevarskaya, N, Ancha V. Baranova, Baranova, Ancha V, Natalia Prevarskaya, Benjamin Beck, Ivanov, Dmitry V, Panchin, Yuri, Ivanov, Dimitri, Prevarskaya, Natalia, Vanden Abeele, Fabien, Bidaux, G, Bidaux, Gabriel, Dmitry V. Ivanov, Beck, B, Panchin, Yuri, V, Roman Skryma, Dmitri Gordienko   +31 more
core   +1 more source

DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling

Aging Cell, Volume 25, Issue 9, September 2026.
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li, Zhen Yang, Wukaiyang Liang, Jie Huang, Tianyi Ji, Hao Nie, Zixin Wan, Yuqi Qiu, Yi Huang, Le Zhang, Cuntai Zhang, Jinhua Yan   +11 more
wiley   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, Volume 293, Issue 18, Page 5481-5513, September 2026.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Studies on ion movements in Malpighian tubules of Locusta migratoria L., with particular reference to their endocrine control [PDF]

, 1990
Intracellular microelectrodes were used in conjunction with ion substitution, agonists and inhibitors of known transport processes and diuretic hormone (DH), to investigate the mechanisms whereby ions cross the basal and apical cell membranes of the ...
Fogg, Kay Elizabeth, Fogg, K.E
core  

CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors.

J Cell Sci, 2021
Arige V, Terry LE, Malik S, Knebel TR, Wagner Ii LE, Yule DI.   +5 more
europepmc   +1 more source