Results 181 to 190 of about 1,340,779 (272)

The Role of Astrocytes in the Inflammatory Response in Neurodiseases

MedComm, Volume 7, Issue 11, November 2026.
Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng, Lepeng Wang, Jia Ouyang, Ruen Liu   +3 more
wiley   +1 more source

Research note: Untargeted metabolomics to understand the impact of controlled atmosphere stunning and electrical stunning on metabolite profiles of early postmortem breast fillet. [PDF]

Poult Sci
Kumar R, Boersma M, Che S, Tushar Z, Raut R, Bourassa DV.   +5 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates. [PDF]

FEBS Lett
Rolfes RJ.
europepmc   +1 more source

From wild to tamed: Reimagining novel crops through omics and local plant diversity

PLANTS, PEOPLE, PLANET, Volume 8, Issue 6, Page 2034-2048, November 2026.
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá, Pablo D. Cárdenas   +1 more
wiley   +1 more source

Inositol Thiophosphates as Inhibitors of Mammalian, Plant, and Fungal Phytases. [PDF]

ACS Chem Biol
Vasegh SE, Cummer R, Meneses J, Kok LV, Finn LM, Nelea V, Dridi L, Keller BG, Reinhardt DP, Castagner B.   +9 more
europepmc   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

An inositol receptor Itr4 coordinates carbon catabolite regulation and virulence in Cryptococcus neoformans. [PDF]

PLoS Biol
Wang Y, Tancer RJ, Wear M, Jackson KM, Zhang Y, Li K, Wang J, Gao YG, Nielsen K, Casadevall A, Xue C.   +10 more
europepmc   +1 more source

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

Small, Volume 22, Issue 61, 2 November 2026.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey, Alexander J. Bryer, Juan R. Perilla   +2 more
wiley   +1 more source

Inositol phosphates: small molecules with a BIG impact on maize embryo development. [PDF]

Plant Physiol
Freed CP, Cullen E.
europepmc   +1 more source