Analytical Methods for Determination of Phytic Acid and Other Inositol Phosphates: A Review [PDF]
Molecules, 2020 From the early precipitation-based techniques, introduced more than a century ago, to the latest development of enzymatic bio- and nano-sensor applications, the analysis of phytic acid and/or other inositol phosphates has never been a straightforward ...
Gregor Marolt, Mitja Kolar
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Towards Improved Bioavailability of Cereal Inositol Phosphates, Myo-Inositol and Phenolic Acids [PDF]
MoleculesCereals are among the foods rich in myo-inositol hexakisphosphate (phytic acid, IP6), lower myo-inositol phosphates (IPx), a wide range of phenolic compounds, as well as vitamins, minerals, oligosaccharides, phytosterols and para-aminobenzoic acid, and ...
Krzysztof Żyła, Aleksandra Duda
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Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, 2022 The first - already published - stage of the project, which conducted optimization of the temperature mashing program, yielded promising results in the form of an increase in the pool of bioactive myo-inositol by 50% in buckwheat wort supplemented with ...
Robert DULIŃSKI, Dagmara PONIEWSKA
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Metabolism of inositol derivatives by the gut microbiome [PDF]
Gut MicrobesThe gut microbiome harbors immense metabolic capacity, much of which is still being uncovered. Recent discoveries have highlighted the ability of gut microbes to metabolize inositol-derived compounds, including free inositols and their phosphorylated ...
Henning Jessen, Thi Phuong Nam Bui
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Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers [PDF]
Nature Communications, 2020 Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate ...
Antonia E. Schantl +21 more
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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates [PDF]
Nature Communications, 2016 Class I histone deacetylase complexes can be activated by inositol phosphates. Here, the authors investigate the stereochemical requirements for activation; use the crystal structure to understand substrate recognition, and suggest an entropically driven
Peter J. Watson +9 more
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Protein pyrophosphorylation by inositol phosphates: a novel post-translational modification in plants? [PDF]
Frontiers in Plant ScienceInositol pyrophosphates (PP-InsPs) are energy-rich molecules harboring one or more diphosphate moieties. PP-InsPs are found in all eukaryotes evaluated and their functional versatility is reflected in the various cellular events in which they take part ...
Yeshambel Emewodih Mihiret +2 more
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The Impact of Phytases on the Release of Bioactive Inositols, the Profile of Inositol Phosphates, and the Release of Selected Minerals in the Technology of Buckwheat Beer Production [PDF]
Biomolecules, 2020 A relatively high concentration of phytate in buckwheat malt, and the low activity of endogenous buckwheat phytases, both of which limit the effective use of substrates (starch, proteins, minerals) for fermentation and yeast metabolism, gives rise to the
Robert Duliński +4 more
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Inositol metabolism as a broad-spectrum antiviral target [PDF]
Frontiers in MicrobiologyInositol plays many important roles in cellular processes through its various derivatives including phosphatidylinositol phosphates. Viruses use phosphatidylinositol phosphates for their replication in multiple processes including entry, formation of ...
Kunlakanya Jitobaom +3 more
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Simultaneous HPLC determination of soluble signaling molecules and metabolic status in neuroblastoma cell cultures [PDF]
Physiological ReportsSeveral laboratories have explored the capacity of the anion exchange chromatography method in evaluating distinct forms of inositol phosphates in a single analytical process.
Natalie Chaves Ferreira +2 more
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