Results 211 to 220 of about 30,119 (260)

Phosphate, inositol and polyphosphates

Biochemical Society Transactions, 2016
Eukaryotic cells have ubiquitously utilized the myo-inositol backbone to generate a diverse array of signalling molecules. This is achieved by arranging phosphate groups around the six-carbon inositol ring. There is virtually no biological process that does not take advantage of the uniquely variable architecture of phosphorylated inositol. In inositol
Thomas M, Livermore, Cristina, Azevedo, Bernadett, Kolozsvari, Miranda S C, Wilson, Adolfo, Saiardi   +4 more
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INOSITOL PHOSPHATE BIOCHEMISTRY

Annual Review of Biochemistry, 1992
PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
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Configuration of Inositol Phosphate in Liver Phosphatidyl Inositol

Nature, 1960
THE hydrolysis of synthetic glycerol 1-(inositol 2-phosphate)1,2 has recently been compared with that of the glycerylphosphoryl inositol isolated from hydrolysates of liver phosphatidyl inositol3. The results suggest that the phosphate group in the original lipid is attached to the 1- or 2-hydroxyl of the myoinositol.
J N, HAWTHORNE, P, KEMP, R B, ELLIS
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Phosphatidylinositol and inositol phosphate metabolism

Journal of Cell Science, 2001
The six carbons that comprise the inositol ring can be phosphorylated in a combinatorial manner, generating a truly astonishing range of inositol phosphates and inositol lipids. Yet, somehow, the cell can distinguish and utilize several of these metabolites to specifically regulate a variety ...
K, Abel, R A, Anderson, S B, Shears
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Rapid Analysis of Inositol Phosphates

Journal of Agricultural and Food Chemistry, 2001
Fast and simple analytical methods for the determination of inositol bis- to hexakisphosphates or only inositol hexakisphosphate in foods and feces are presented. The methods are both faster and simpler with regard to analytical detection and sample pretreatment as compared to previously reported methods. The samples are pretreated using extraction and
N G, Carlsson, E L, Bergman, E, Skoglund, K, Hasselblad, A S, Sandberg   +4 more
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Mass measurement of inositol phosphates

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989
This review summarises the methods available for the mass measurement of inositol phosphates, i.e., use of radioactive inositol lipid precursors, optical techniques, gas chromatography, mass spectrometry, nuclear magnetic resonance, fast atom bombardment and assays specific for Ins(1,4,5)P3.
Palmer, S, Wakelam, M J
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Paosphorothioate Analogues of Inositol Phosphates

Phosphorus, Sulfur, and Silicon and the Related Elements, 1990
Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan Cooke, Leroy James, Stefan Nahorski, Barry Potter   +3 more
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Inositol Phosphate Metabolism and Signal Transduction

American Review of Respiratory Disease, 1990
Activation of a variety of cell surface receptors results in a biphasic increase in the cytoplasmic Ca2+ concentration, due to the release or mobilization of intracellular Ca2+ stores and to the entry of Ca2+ from the extracellular space. Stimulation of these same receptors also results in the hydrolysis of the minor plasma membrane phospholipid ...
A R, Hughes, D A, Horstman, H, Takemura, J W, Putney   +3 more
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Gradient ion chromatography of inositol phosphates

Analytical Biochemistry, 1988
Inositol phosphates including phytic acid were separated in 30 min by gradient ion chromatography with postcolumn derivatization. All four pentakisphosphates were resolved, while four tetrakisphosphate peaks were detected. The limits of detection for all polyphosphates, including tris- and bisphosphates, were between 1 and 2 nmol.
B Q, Phillippy, J M, Bland
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Inositol Phosphate Metabolism During Myocardial Ischemia

Journal of Molecular and Cellular Cardiology, 1997
Inositol phosphate release in intact heart in response to norepinephrine involves primarily release of inositol(1,4)bisphosphate (Ins(1,4)P2) rather than inositol(1,4,5)trisphosphate (Ins(1,4,5)P3) but Ins(1,4,5)P3 release predominates under conditions of post-ischemic reperfusion.
E A, Woodcock, K A, Lambert, T, Phan, A N, Jacobsen   +3 more
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