Results 211 to 220 of about 11,589 (250)
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Rapid Analysis of Inositol Phosphates
Journal of Agricultural and Food Chemistry, 2001Fast and simple analytical methods for the determination of inositol bis- to hexakisphosphates or only inositol hexakisphosphate in foods and feces are presented. The methods are both faster and simpler with regard to analytical detection and sample pretreatment as compared to previously reported methods. The samples are pretreated using extraction and
Eva-Lotta Bergman +4 more
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Inositol Phosphates in the Nucleus
Science, 2000The inositol signaling pathways in the cytoplasm are well characterized. In a Perspective, Chi and Crabtree now explain how similar inositol pathways operate in the nucleus to switch gene expression on and off. One of the key players is the kinase Ipk2p, which might stabilize components of a transcription complex ( Odom et al.).
Gerald R. Crabtree, Tian Chi
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Inositol phosphates and cell signalling
Nature, 1989Inositol 1,4,5-trisphosphate is a second messenger which regulates intracellular calcium both by mobilizing calcium from internal stores and, perhaps indirectly, by stimulating calcium entry. In these actions it may function with its phosphorylated metabolite, inositol 1,3,4,5-tetrakisphosphate. The subtlety of calcium regulation by inositol phosphates
Michael J. Berridge, Robin F. Irvine
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The Metabolism of Inositol Phosphates [PDF]
, 1988 Phosphatidylinositols are phospholipid precursors of a series of inositol phosphates. Several inositol phosphates function as messenger molecules that evoke responses in cells following stimulation by extracellular agonists. While many different compounds are formed, the functions of only a few are understood.
Philip W. Majerus +4 more
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Mass measurement of inositol phosphates
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989This review summarises the methods available for the mass measurement of inositol phosphates, i.e., use of radioactive inositol lipid precursors, optical techniques, gas chromatography, mass spectrometry, nuclear magnetic resonance, fast atom bombardment and assays specific for Ins(1,4,5)P3.
Palmer, S, Wakelam, M J
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A bioautographic method for the identification of inositol and inositol phosphate
Analytical Biochemistry, 1962Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
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Methods for the analysis of inositol phosphates
Analytical Biochemistry, 1989Interest in the inositol phospholipids was stimulated by the simultaneous discoveries that the products of hydrolysis of these lipids could serve as messengers to activate to synergistic signaling pathways in hormonally responsive cells, namely, inositol 1,4,5-trisphosphate which causes the release of Ca2+ from intracellular stores and diacylglycerol ...
Michael A. Beaven, Nicholas M. Dean
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ChemInform Abstract: Phosphorothioate Analogues of Inositol Phosphates
ChemInform, 1990Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan M. Cooke +3 more
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Stereoselective synthesis of inositol phosphates [PDF]
Pure and Applied Chemistry, 1990 Abstract
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Inositol Phosphates and Their Metabolism in Plants
1996The discovery that plasma membrane phosphoinositides mediate cellular responses to external signals has led to tremendous interest in the structure and metabolism of phosphoinositides and inositol phosphates. The role of inositol1,4,5-trisphosphate [Ins(1,4,5)P3] as a mediator of receptor-initiated changes in intracellular calcium is well characterized
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