Results 71 to 80 of about 30,119 (260)

Binding of inositol phosphates to arrestin [PDF]

FEBS Letters, 1991
Arrestin binds to phosphorylated rhodopsin in its light‐activated form (metarhodopsin II), blocking thereby its interaction with the G‐protein, transducin. In this study, we show that highly phosphorylated forms of inositol compete against the arrestin‐rhodopsin interaction.
Palczewski, Krzysztof, Pulvermüller, Alexander, Buczylko, Janina, Gutmann, Caroline, Hofmann, Klaus Peter   +4 more
openaire   +2 more sources

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

Advanced Science, EarlyView.
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter, Verena Gaugler, Sara Christina Stolze, Riya Ghosh, Akhila Jayamon, Ranjana Yadav, Felix Wollensack, Debabrata Laha, Hirofumi Nakagami, Gabriel Schaaf, Henning Jacob Jessen   +10 more
wiley   +1 more source

Di‐myo‐inositol‐1, 1′‐phosphate: A new inositol phosphate isolated from Pyrococcus woesei

FEBS Letters, 1992
A new inositol derivative could be isolated from the Archaeum Pyrococcus woesei and identified as di‐myo‐inositol‐1,1′‐phosphate by 1H, 31P NMR spectroscopy, mass spectrometry and thin layer chromatograpy. In P. woesel, this inositol phosphate represents the dominant counterion of K+ which ranges from 500 to 600 mM. The role of the potassium salt of di‐
Scholz, Stefan, Sonnenbichler, Johann, Schäfer, Wolfram, Hensel, Reinhard   +3 more
openaire   +2 more sources

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

Advanced NanoBiomed Research, EarlyView.
The incubation of primary astrocytes with fAuNCs‐BSA induces: (A) long‐term effects including fAuNCs‐BSA internalization, red cell fluorescence, differentiation, upregulation of Ca2+ signaling, Cl‐current, and cell volume regulation. B) Short‐term (200 ms) stimulation with UV LED light increases in Ca2+ signaling and inhibition of K+ current. Astrocyte
Roberta Fabbri, Karima Jeneh Perry, Emanuela Saracino, Chiara Lazzarini, Anna Mariano, Diletta Spennato, Maria Grazia Mola, Maria Grazia Raucci, Alessandro Kovtun, Marianna Barbalinardo, Giorgia Conte, Denis Gentili, Marco Caprini, Vincenzo Palermo, Roberto Zamboni, Luigi Ambrosio, Wolfgang Losert, Andrea Candini, Grazia Paola Nicchia, Raj K. Gupta, Valentina Benfenati, Shashi P. Karna   +21 more
wiley   +1 more source

Biosynthesis and possible functions of inositol pyrophosphates in plants

Frontiers in Plant Science, 2015
Inositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is
Sarah Phoebe Williams, Glenda E Gillaspy, Imara Yasmin Perera   +2 more
doaj   +1 more source

The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade [PDF]

, 2005
Signaling pathways mediating the divergent effects of FSH and LH on aromatase in immature rat granulosa cells were studied by infecting cells with increasing amounts of adenoviral vectors for the hLHR or hFSHR.
Ascoli, Ascoli, Ascoli, Bebia, Bustin, Carvalho, Cohen, Conti, Cunningham, De Vivo, Devi, Dias, Farfel, Fitzpatrick, Fitzpatrick, Fitzpatrick, Francesc Xavier Donadeu, Galway, Gether, Gonzalez-Robayna, Gonzalez-Robayna, Graziano, Hickey, Hipkin, Hipkin, Hirakawa, Hirakawa, Jo, Kaminski t, Akinola, Kenakin, Krishnamurthy, Liri, Mario Ascoli, Min, Morris, Morris, Nechamen, Pierce, Pierce, Piquette, Richards, Richards, Richards, Richards, Salvador, SAS Institute, Segaloff, Segaloff, Segaloff, Shi, Shinohara, Simoni, Simpson, Somers, Steiner, Tapanainen, Terrillon, Themmen, Uilenbroek, Vassart, Wang, Wang, Whaley, Yong, Yoshino, Zeleznik, Zhu   +66 more
core   +1 more source

Creation of a Pseudotsuga menziesii nucellus cell suspension culture system to produce proteins involved in reproduction

Applications in Plant Sciences, EarlyView.
Abstract Premise Cell suspension cultures of Douglas‐fir (Pseudotsuga menziesii) nucellus were created to overcome phenological limitations to the in situ study of bioactive proteins within and secreted by nucellar cells. Methods Proteins isolated from the cell suspension culture medium were analyzed using mass spectrometry, as were Douglas‐fir post ...
Andrea Coulter, YuQi Li, Julia Lakhani, Natalie Prior, Patrick von Aderkas   +4 more
wiley   +1 more source

Generation of inositol polyphosphates through a phospholipase C-independent pathway involving carbohydrate and sphingolipid metabolism in Trypanosoma cruzi

mBio
Inositol phosphates are involved in a myriad of biological roles and activities such as Ca2+ signaling, phosphate homeostasis, energy metabolism, and disease pathogenicity.
Mayara S. Bertolini, Sabrina E. Cline, Miguel A. Chiurillo, Brian S. Mantilla, Aharon Eidex, Logan P. Crowe, Danye Qiu, Henning J. Jessen, Adolfo Saiardi, Roberto Docampo   +9 more
doaj   +1 more source

Activation of phospholipase C beta4 by heterotrimeric GTP-binding proteins [PDF]

, 1994
Transient transfection assays were used to determine how the activity of phospholipase C beta 4, which is preferentially expressed in retina, was regulated.
Jiang, Huiping, Simon, Melvin I., Wu, Dianqing   +2 more
core