Results 71 to 80 of about 30,835 (333)

Myoinositol in Autoimmune Thyroiditis

Frontiers in Endocrinology, 2022
Myoinositol (Myo) is an isoform of inositol, a cyclic polyol with 6 hydroxyl groups. Myo is mainly derived from dietary intake while its endogenous production is generated from glucose by enzymatic reactions.
Sabrina Rosaria Paparo, Silvia Martina Ferrari, Armando Patrizio, Giusy Elia, Francesca Ragusa, Chiara Botrini, Eugenia Balestri, Fabrizio Guarneri, Salvatore Benvenga, Salvatore Benvenga, Salvatore Benvenga, Alessandro Antonelli, Poupak Fallahi   +12 more
doaj   +1 more source

Inositol phosphate multikinase dependent transcriptional control [PDF]

Advances in Biological Regulation, 2017
Production of lipid-derived inositol phosphates including IP4 and IP5 is an evolutionarily conserved process essential for cellular adaptive responses that is dependent on both phospholipase C and the inositol phosphate multikinase Ipk2 (also known as Arg82 and IPMK). Studies of Ipk2, along with Arg82 prior to demonstrating its IP kinase activity, have
Ace J, Hatch, Audrey R, Odom, John D, York   +2 more
openaire   +2 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives

Natural Product Reports, 2007
This review highlights inositol polyphosphate- and phosphatidylinositol-based small molecule probes that have advanced our understanding of intracellular signalling.
Conway, Stuart J., Miller, Gavin J.
openaire   +3 more sources

Binding of inositol phosphates to arrestin [PDF]

FEBS Letters, 1991
Arrestin binds to phosphorylated rhodopsin in its light‐activated form (metarhodopsin II), blocking thereby its interaction with the G‐protein, transducin. In this study, we show that highly phosphorylated forms of inositol compete against the arrestin‐rhodopsin interaction.
Palczewski, Krzysztof, Pulvermüller, Alexander, Buczylko, Janina, Gutmann, Caroline, Hofmann, Klaus Peter   +4 more
openaire   +2 more sources

The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade [PDF]

, 2005
Signaling pathways mediating the divergent effects of FSH and LH on aromatase in immature rat granulosa cells were studied by infecting cells with increasing amounts of adenoviral vectors for the hLHR or hFSHR.
Ascoli, Ascoli, Ascoli, Bebia, Bustin, Carvalho, Cohen, Conti, Cunningham, De Vivo, Devi, Dias, Farfel, Fitzpatrick, Fitzpatrick, Fitzpatrick, Francesc Xavier Donadeu, Galway, Gether, Gonzalez-Robayna, Gonzalez-Robayna, Graziano, Hickey, Hipkin, Hipkin, Hirakawa, Hirakawa, Jo, Kaminski t, Akinola, Kenakin, Krishnamurthy, Liri, Mario Ascoli, Min, Morris, Morris, Nechamen, Pierce, Pierce, Piquette, Richards, Richards, Richards, Richards, Salvador, SAS Institute, Segaloff, Segaloff, Segaloff, Shi, Shinohara, Simoni, Simpson, Somers, Steiner, Tapanainen, Terrillon, Themmen, Uilenbroek, Vassart, Wang, Wang, Whaley, Yong, Yoshino, Zeleznik, Zhu   +66 more
core   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Biosynthesis and possible functions of inositol pyrophosphates in plants

Frontiers in Plant Science, 2015
Inositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is
Sarah Phoebe Williams, Glenda E Gillaspy, Imara Yasmin Perera   +2 more
doaj   +1 more source

Phosphorus in pig diets [PDF]

, 2006
Pig feed is mainly based on cereals where phosphorus (P) is mostly present in inositol hexaphosphate (IP6), which is not readily available to monogastric animals.
Lyberg, Karin
core  

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source