Results 81 to 90 of about 11,589 (250)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

ELECTROPHORESIS, EarlyView.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont, María Vergara‐Barberán, Enrique Javier Carrasco‐Correa   +2 more
wiley   +1 more source

Dissecting the Hydrolytic Activities of Sarcoplasmic Reticulum ATPase in the Presence of Acetyl Phosphate [PDF]

J Biol Chem . 2002 Oct 11;277(41):38127-32
Sarcoplasmic reticulum vesicles and purified Ca$^{2+}$-ATPase hydrolyze acetyl phosphate both in the presence and absence of Ca$^{2+}$. The Ca$^{2+}$-independent activity was fully sensitive to vanadate, insensitive to thapsigargin, and proceeded without accumulation of phosphorylated enzyme.
arxiv   +1 more source

Synthetic Pores as Sensors: Focus on Zinc Filters for IP7 and Phytate Contents in Lentils, Almonds, and Soybeans

CHIMIA, 2008
Recent experimental evidence confirms synthetic pores as operational multicomponent sensors in complex matrices. This work in practice is summarized, with emphasis on topics of current concern which exemplify the use of enzymes as signal ...
Sara M. Butterfield, Stefan Matile
doaj   +1 more source

Inositol Phosphates: A Remarkably Versatile Enzyme [PDF]

Current Biology, 2002
Ins(3,4,5,6)P(4) is an inhibitor of Ca(2+)-activated Cl(-) channels, but further understanding has been hindered by ignorance of how it is made in cells. It now transpires that one protein with ATP-dependent kinase and phosphatase activities interconverts Ins(3,4,5,6)P(4) and Ins(1,3,4,5,6)P(5), as well as several other inositol polyphosphates.
openaire   +3 more sources

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer

Frontiers in Oncology, 2017
Calcium is a critical regulator of cell death pathways. One of the most proximal events leading to cell death is activation of plasma membrane and endoplasmic reticulum-resident calcium channels.
Jessica J. Chen, Darren Boehning
doaj   +1 more source

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults

iMetaOmics, EarlyView.
Understanding the skin microbiome is crucial for elucidating its role in health and disease. However, comprehensive studies on the genetic and functional diversity of the skin microbiome in individuals living in extreme environments remain scarce. This work explores the unique characteristics and functional adaptations of the plateau skin microbiome ...
Yi Liu, Zhiming Li, Chao Zhang, Bo Li, Weiwei Jiang, Hang Li, Lei Zhang, Hefu Zhen, Shujun Bao, Xiong Li, Yinuo Liu, Xianzhen Chen, Jinxia Du, Jingjing Xia, Jiucun Wang, Ruijin Guo, Yuzhe Sun, Bo Pan, Wenzhi Lei, Liang Xiao, Jin Zhao, Xin Jin, Wenwei Zhang, Xiaogang Liu, Jian Wang, Min Chen, Wanqing Liao, Wenjie Fang, Chao Nie, Weihua Pan   +29 more
wiley   +1 more source

Simulating the transport of dissolved ammonium-nitrogen and phosphate-phosphorous to streams using artificial neural network (ANN) [PDF]

arXiv, 2020
The export of agricultural fertilizers to streams results in untold harms to downstream water quality and thus ecosystem. Understanding and simulating the export of these chemicals is the first step to control their transport to streams. In this paper, the export of ammonium and phosphate, two major contaminants resulted from agricultural activities ...
arxiv  

Inositol Phosphates and their Biological Effects

Biomedical and Pharmacology Journal, 2014
The paper is dedicated to data analysis on inositol phosphates nature distribution, structure and biological functions as well as enzymes phytases capable to hydrolyze these hardly digestible compounds and their complexes. Pharmaceutical application of inositol phosphates in treatment and prevention of various inflammatory and cancer diseases is ...
Margarita R. Sharipova, Inna B. Chastukhina, L. R. Valeeva, Alyia Damirovna Suleimanova, Nelly P. Balaban   +4 more
openaire   +5 more sources