Results 101 to 110 of about 98,783 (245)

Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules [PDF]

Journal of the Indian Institute of Science, 2017
Inositol pyrophosphates (PP-IPs) are a class of energy-rich signalling molecules found in all eukaryotic cells. These are derivatives of inositol that contain one or more diphosphate (or pyrophosphate) groups in addition to monophosphates. The more abundant and best studied PP-IPs are diphosphoinositol pentakisphosphate (IP7) and bis-diphosphoinositol ...
Shah, Akruti, Ganguli, Shubhra, Sen, Jayraj, Bhandari, Rashna   +3 more
openaire   +2 more sources

The regulation of carotenoid formation in tomato fruit [PDF]

, 2017
Carotenoid biosynthesis in plants includes a complex series of desaturation/isomerisation reactions, catalysed by four independent enzymes. In bacteria and fungi one desaturase/isomerase enzyme completes the same series of reactions. In the present study,
Adam, Avendano-Vazquez, Beltran, Bird, Bramley, Breitenbach, Brown, Chen, Davuluri, Demmig-Adams, Enfissi, Fantini, Fraser, Fraser, Fraser, Fraser, Fraser, Fraser, Fraser, Fraser, Fraser, Gemmecker, Hirschberg, Isaacson, Isaacson, Kachanovsky, Kobayashi, Krinsky, Linden, Long, Lyska, Misawa, Nogueira, Park, Perez-Fons, Pulido, Ramel, Rao, Romer, Ronen, Sandmann, Sandmann, Schaub, Schwartz, Shumskaya, Story, Walley, Ye, Yu, Zechmeister, Zhang, Zhou   +51 more
core   +1 more source

Phosphate Resupply Differentially Impacts the Shoot and Root Proteomes of Arabidopsis thaliana Seedlings

Plant, Cell &Environment, Volume 49, Issue 3, Page 1598-1616, March 2026.
ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith, Lauren E. Grubb, Kirsten H. Benidickson, Devang Mehta, William C. Plaxton, R. Glen Uhrig   +5 more
wiley   +1 more source

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase [PDF]

, 2014
The Vps34 (vacuolar protein sorting 34) class III PI3K (phosphoinositide 3-kinase) phosphorylates PtdIns (phosphatidylinositol) at endosomal membranes to generate PtdIns(3)P that regulates membrane trafficking processes via its ability to recruit a ...
Alessi, Dario R., Bago, Ruzica, Cross, Darren, Davies, Paul, Ganley, Ian G., Malik, Nazma, Munson, Michael J., Prescott, Alan R., Shpiro, Natalia, Sommer, Eeva, Ward, Richard   +10 more
core   +3 more sources

Climate change and the antinutrient–antioxidant puzzle in common bean seeds

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1451-1456, February 2026.
Abstract Non‐proteinaceous and proteinaceous antinutrients in common bean (Phaseolus vulgaris L.) seeds can negatively affect human nutrition by reducing mineral bioavailability and impairing protein digestibility during digestion, respectively. However, many of these compounds also possess strong antioxidant properties that can help protect the plant ...
Juan Vorster, Eleonora Cominelli, Francesca Sparvoli, Alessia Losa, Tea Sala, Karl Kunert   +5 more
wiley   +1 more source

Pectic enzymes as potential enhancers of ascorbic acid production through the D-galacturonate pathway in Solanaceae [PDF]

, 2018
The increase of L-Ascorbic Acid (AsA) content in tomato (Solanum lycopersicum) is a common goal in breeding programs due to its beneficial effect on human health.
Barone, Amalia, Bellincampi, Daniela, Lionetti, Vincenzo, Raiola, Assunta, Rigano, Maria Manuela   +4 more
core   +2 more sources

A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis [PDF]

, 2021
Eric Land, Caitlin Cridland, Branch Craige, Anna E. Dye, Sherry B. Hildreth, Richard F. Helm, Glenda E. Gillaspy, Imara Y. Perera   +7 more
openalex   +1 more source

Atypical p38 Kinase Signaling in Retinal Vascular Damage and Recovery

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
Using an oxygen‐induced retinopathy model, we demonstrate that Tab1‐dependent atypical p38 activation contributes to retinal vascular injury. Genetic blockade of this pathway protects against pathological neovascularization by modulating transcriptional programs.
Lillian Schulz, Abby E. Young, Fang Liu, Sanjana Gattineni, Sneha S. Ghosh, Eugene Douglass, Heike Kroeger, S. Priya Narayanan, Neil J. Grimsey   +8 more
wiley   +1 more source

β-Lapachone Regulates Mammalian Inositol Pyrophosphate Levels in an NQO1- and Oxygen-dependent Manner

bioRxiv, 2022
Inositol pyrophosphates (PP-InsPs) are energetic signalling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis.
Verena B. Eisenbeis, Danye Qiu, Lisa Strotmann, Guizhen Liu, Isabel Prucker, Kevin Ritter, Christoph Loenarz, A. Saiardi, H. Jessen   +8 more
semanticscholar   +1 more source

Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities

Frontiers in Cellular and Infection Microbiology, 2019
Invasive fungal pathogens cause more than 300 million serious human infections and 1.6 million deaths per year. A clearer understanding of the mechanisms by which these fungi cause disease is needed to identify novel targets for urgently needed therapies.
Sophie Lev, Sophie Lev, Sophie Lev, Cecilia Li, Cecilia Li, Desmarini Desmarini, Desmarini Desmarini, Desmarini Desmarini, Tania C. Sorrell, Tania C. Sorrell, Tania C. Sorrell, Adolfo Saiardi, Julianne T. Djordjevic, Julianne T. Djordjevic, Julianne T. Djordjevic   +14 more
doaj   +1 more source