Results 91 to 100 of about 13,047 (201)
Mechanisms and regulation of the polyphosphate/factor XII-driven contact system in thrombosis and hemostasis [PDF]
Blood coagulation leading to fibrin formation is essential to prevent loss of blood (hemostasis), but can also contribute to occlusion of vessels (thrombosis).
Labberton, Linda
core +1 more source
Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing
Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz +5 more
wiley +1 more source
Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? [PDF]
The regulation of ion channels by anionic phospholipids is currently very topical. An outstanding issue is whether phosphatidylinositol 4,5-diphosphate and related species act as true second messengers in signaling or behave in a manner analogous to an ...
Clapp, LH +4 more
core +1 more source
Clostridium perfringens forms heat‐resistant spores that complicate food safety. Physical methods (thermal processing, HPP, vacuum cooling, ozone treatments) and chemical interventions (natural antimicrobials, phosphates, nitrate/nitrite, organic acids) reduce vegetative cells and spores, though spore resistance remains a major challenge in food and ...
Deepak Subedi +7 more
wiley +1 more source
Inositol Pyrophosphates as Versatile Metabolic Messengers
Discovered in 1993, inositol pyrophosphates are evolutionarily conserved signaling metabolites whose versatile modes of action are being increasingly appreciated. These include their emerging roles as energy regulators, phosphodonors, steric/allosteric regulators, and G protein–coupled receptor messengers.
Latika, Nagpal +3 more
openaire +2 more sources
Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies
Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley +1 more source
Cells face major changes in demand for and supply of inorganic phosphate (Pi). Pi is often a limiting nutrient in the environment, particularly for plants and microorganisms.
Sisley Austin, Andreas Mayer
doaj +1 more source
PHR1 mediates rapid high light responses and acclimation to high photosynthetic activity
SUMMARY Changing light intensity requires immediate metabolic adjustment which involves reprogramming of both plastidial and nuclear gene expression, but the signaling pathways behind such responses are not fully understood. Here we report that an increase in light intensity causes fluctuations of Pi levels in the chloroplasts of Arabidopsis thaliana ...
Lukas Ackermann +7 more
wiley +1 more source
Structural basis of phosphate export by human XPR1
Phosphorus in crucial for all living organisms. In vertebrate, cellular phosphate homeostasis is partly controlled by XPR1, a poorly characterized inositol pyrophosphate-dependent phosphate exporter.
Qixian He +7 more
doaj +1 more source
In a short‐term pot experiment, three legume‐based crop rotations are being tested for their effects on the P cycle and P use efficiency compared to maize monoculture. Legume‐based crop rotations stimulate the P cycle by increasing acid phosphatase activity and carboxylate exudation.
Michelle Natalie Herrmann +6 more
wiley +1 more source

