Results 91 to 100 of about 58,667 (143)

VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP₈ and Jasmonate-Dependent Defenses in Arabidopsis [PDF]

, 2015
Diphosphorylated inositol polyphosphates, also referred to as inositol pyrophosphates, are important signaling molecules that regulate critical cellular activities in many eukaryotic organisms, such as membrane trafficking, telomere maintenance, ribosome
Johnen, P, De Campos, MKF, Zheng, N, Freyer, M, Feussner, I, Laha, D, Gaugler, P, Iven, T, Azevedo, C, Weiss, M, Steenbergen, M, Jessen, HJ, Saiardi, A, Mao, H, Capolicchio, S, Van Wees, SCM, Schaaf, G, Dynowski, M   +17 more
core   +1 more source

Inositol pyrophosphate synthesis by diphosphoinositol pentakisphosphate kinase-1 is regulated by phosphatidylinositol(4,5)bisphosphate

, 2018
The 5-diphosphoinositol pentakisphosphate (5-InsP7) and bisdiphosphoinositol tetrakisphosphate (InsP8) are “energetic” inositol pyrophosphate signaling molecules that regulate bioenergetic homeostasis.
Nair, Vasudha S., Henning J. Jessen, Huanchen Wang, Janoshazi, Agnes K., Wang, Huanchen, Shears, Stephen B., Stephen B. Shears, Gu, Chunfang, Jessen, Henning, Chunfang Gu, Vasudha S. Nair, Agnes K. Janoshazi   +11 more
core   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio
Dimethylsulfoxide (DMSO) is widely used as a solvent or as a carrier when screening for biologic activity of various chemicals, but results need to be interpreted carefully due to its intrinsic toxicity.
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
doaj   +1 more source

Pyro-Technic Control of Metabolism

, 2011
An inositol pyrophosphate controls cellular energetics by regulating the expression of glycolytic enzymes.
Denton, Richard M., Irvine, Robin F., Richard M. Denton, Robin F. Irvine   +3 more
core   +1 more source

Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues

, 2016
The inositol pyrophosphate messengers (PP-InsPs) are emerging as an important class of cellular regulators. These molecules have been linked to numerous biological processes, including insulin secretion and cancer cell migration, but how they trigger ...
Wu, Mingxuan, Wang, Huanchen, Veiga, Nicolás, Anastasia Hager, Dorothea Fiedler, Nicolás Veiga, Hager, Anastasia, Nathaniel W. Brown, Brown, Jr., Nathaniel W., Huanchen Wang, Shears, Stephen B., Fiedler, Dorothea, Mingxuan Wu, Stephen B. Shears   +13 more
core   +1 more source

Analysis of Inositol Phosphates via Polyacrylamide Gel Electrophoresis (PAGE)

Polyacrylamide gel electrophoresis (PAGE) is a versatile technique widely used in molecular biology for the separation of biomolecules based on size and charge.
Saiardi, Adolfo, Fedeli, Valeria
core   +1 more source

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in <i>S. pombe</i>. [PDF]

J Fungi (Basel), 2022
Kuenzel NA, Alcázar-Román AR, Saiardi A, Bartsch SM, Daunaraviciute S, Fiedler D, Fleig U.   +6 more
europepmc   +1 more source

Biochemical Characterization of Arabidopsis Enzymes Involved in Inositol Pyrophosphate Biosynthesis

, 2019
To compensate for the sessile nature of plants, thousands of years of evolution have led to the development of many sophisticated signaling pathways that help plants sense and respond appropriately to different environmental cues.
Adepoju, Olusegun Adeboye
core  

Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling. [PDF]

Biomed Pharmacother, 2023
Qi J, Cheng W, Gao Z, Chen Y, Shipton ML, Furkert D, Chin AC, Riley AM, Fiedler D, Potter BVL, Fu C.   +10 more
europepmc   +1 more source

Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP₇ metabolism in the enteric nervous system. [PDF]

J Biol Chem, 2023
Ito M, Fujii N, Kohara S, Hori S, Tanaka M, Wittwer C, Kikuchi K, Iijima T, Kakimoto Y, Hirabayashi K, Kurotaki D, Jessen HJ, Saiardi A, Nagata E.   +13 more
europepmc   +1 more source