Results 111 to 120 of about 5,995 (168)

Inositol pyrophosphates in cell death and life [PDF]

Cell Cycle, 2011
Michael A, Koldobskiy, Solomon H, Snyder
openaire   +2 more sources

Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1

Nature Communications
Inorganic phosphate (Pi) has essential metabolic and structural roles in living organisms. The Pi exporter, XPR1/SLC53A1, is critical for cellular Pi homeostasis.
Qinyu Zhu, Madeleine F. Yaggi, Nikolaus Jork, Henning J. Jessen, Melinda M. Diver   +4 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

Nature Communications
Inositol pyrophosphates (PP-InsPs) are eukaryotic nutrient messengers. The N-terminal kinase domain of diphosphoinositol pentakisphosphate kinase (PPIP5K) generates the messenger 1,5-InsP8, the C-terminal phosphatase domain catalyzes PP-InsP breakdown ...
Pierre Raia, Kitaik Lee, Simon M. Bartsch, Felix Rico-Resendiz, Daniela Portugal-Calisto, Oscar Vadas, Vikram Govind Panse, Dorothea Fiedler, Michael Hothorn   +8 more
doaj   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio
Dimethylsulfoxide (DMSO) is widely used as a solvent or as a carrier when screening for biologic activity of various chemicals, but results need to be interpreted carefully due to its intrinsic toxicity.
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
doaj   +1 more source

Arabidopsis PFA-DSP-Type Phosphohydrolases Target Specific Inositol Pyrophosphate Messengers. [PDF]

Biochemistry, 2022
Gaugler P, Schneider R, Liu G, Qiu D, Weber J, Schmid J, Jork N, Häner M, Ritter K, Fernández-Rebollo N, Giehl RFH, Trung MN, Yadav R, Fiedler D, Gaugler V, Jessen HJ, Schaaf G, Laha D.   +17 more
europepmc   +1 more source

The Inositol Pyrophosphate Biosynthetic Pathway of <i>Trypanosoma cruzi</i>. [PDF]

ACS Chem Biol, 2021
Mantilla BS, Amaral LDD, Jessen HJ, Docampo R.   +3 more
europepmc   +1 more source

New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1. [PDF]

FASEB J, 2021
Zong G, Jork N, Hostachy S, Fiedler D, Jessen HJ, Shears SB, Wang H.   +6 more
europepmc   +1 more source

Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line. [PDF]

Proc Natl Acad Sci U S A, 2021
Gu C, Liu J, Liu X, Zhang H, Luo J, Wang H, Locasale JW, Shears SB.   +7 more
europepmc   +1 more source

Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors. [PDF]

PLoS ONE, 2017
Brandi M Baughman, Huanchen Wang, Yi An, Dmitri Kireev, Michael A Stashko, Henning J Jessen, Kenneth H Pearce, Stephen V Frye, Stephen B Shears   +8 more
doaj   +1 more source