A new model to describe the physics of VOPO [PDF]
In the past different models for the magnetic salt vanadyl pyrophosphate (VOPO) were discussed. Neither a spin ladder nor an alternating chain are capable to describe recently measured magnetic excitations. In this paper we propose a 2D model that fits better to experimental observations.
arxiv +1 more source
Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair [PDF]
Inositol pyrophosphates, such as diphosphoinositol pentakisphosphate (IP7), are water-soluble inositol phosphates that contain high energy diphosphate moieties on the inositol ring.
Bhandari, Rashna+3 more
core +1 more source
Cigarette Smoke (CS) and Nicotine Delay Neutrophil Spontaneous Death via Suppressing Production of Diphosphoinositol Pentakisphosphate [PDF]
Diphosphoinositol pentakisphosphate (InsP7), a higher inositol phosphate containing energetic pyrophosphate bonds, is beginning to emerge as a key cellular signaling molecule.
Bajrami, Besnik+10 more
core +1 more source
A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut [PDF]
Dietary InsP6 can modulate eukaryotic cell proliferation and has complex nutritive consequences, but its metabolism in the mammalian gastrointestinal tract is poorly understood.
Abrahamse+38 more
core +2 more sources
An allosteric model of the inositol trisphosphate receptor with nonequilibrium binding [PDF]
The inositol trisphosphate receptor (IPR) is a crucial ion channel that regulates the Ca$^{2+}$ influx from the endoplasmic reticulum (ER) to the cytoplasm. A thorough study of the IPR channel contributes to a better understanding of calcium oscillations and waves.
arxiv +1 more source
Identification and characterization of evolutionarily conserved inositol pyrophosphate phosphohydrolases in plants [PDF]
Inositol phosphates (InsPs), phosphate esters of myo-inositol, are cellular regulators with critical roles in a wide range of cellular processes in eukaryotes.
Gaugler, Philipp
core +1 more source
Role of transporters in regulating mammalian intracellular inorganic phosphate
This review summarizes the current understanding of the role of plasma membrane transporters in regulating intracellular inorganic phosphate ([Pi]In) in mammals. Pi influx is mediated by SLC34 and SLC20 Na+-Pi cotransporters.
Michael L. Jennings
doaj +1 more source
Effect of sodium pyrophosphate and understanding microstructure of aqueous LAPONITE(R) dispersion using dissolution study [PDF]
We investigate physical origin of ergodicity breaking in an aqueous colloidal dispersion of synthetic hectorite clay, LAPONITE(R), by performing dissolution and rheological experiments with monovalent salt and tetrasodium pyrophosphate solution. We also study the effect of interface, nitrogen and paraffin oil on the same.
arxiv +1 more source
Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence [PDF]
Fungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP3 to inositol pyrophosphate, PP-IP5/IP7, which is essential for virulence of Cryptococcus neoformans.
Desmarini, D+5 more
core +2 more sources
Photocaged inositol-pyrophosphates offer a tool to study cellular signalling, but their challenging synthesis has precluded any biological studies so far.
Igor Pavlovic+11 more
doaj +1 more source