Results 141 to 150 of about 86,215 (260)
mBio, 2015 Inositol pyrophosphates (PP-IPs) comprising inositol, phosphate, and pyrophosphate (PP) are essential for multiple functions in eukaryotes. Their role in fungal pathogens has never been addressed.
Sophie Lev +8 more
doaj +1 more source
A theoretical and experimental NMR study of the prototropic tautomerism of tris(tetrabutylammonium) hydrogen pyrophosphate salt in solution and in the solid-state [PDF]
, 2015 The structure of tris(tetrabutylammonium)hydrogen pyrophosphate(HPP) has been studied in solution and in the solid-state by 31P NMR. GIAO/DFT calculations of the isolated molecule in its open and closed conformations, of their water complexes and the ...
Alkorta, Ibon +3 more
core +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 2, January 2025.ABSTRACT The hypoxic microenvironment is crucial for tumour cell growth and invasiveness. Tumour tissue results from adaptation to reduced oxygen availability. Hypoxia first activates pro‐angiogenic signals for alleviation. Pathologic, tumour angiogenesis maintains hypoxia, impairing treatment outcomes. Vessel normalisation requires physioxia.
Sabina Koj +6 more
wiley +1 more source
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner [PDF]
, 2023 Inositol pyrophosphates (PP-InsPs) are energetic signaling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis.
Eisenbeis, Verena B +12 more
core
Pyrophosphate Groups in Liquid Crystalline Phases of the DNA [PDF]
arXiv, 2008 We study electrostatic interaction between molecules of the DNA in which a number of phosphate groups of the sugar-phosphate backbone are exchanged for the pyrophosphate ones. We employ a model in which the DNA is considered as a one-dimensional lattice of dipoles and charges corresponding to base pairs and (pyro)phosphate groups, respectively.
arxiv
Physiologia Plantarum, Volume 177, Issue 1, January/February 2025.Abstract In the context of climate changing environments, microalgae can be excellent organisms to understand molecular mechanisms that activate survival strategies under stress. Chlamydomonas reinhardtii signalling mutants are extremely useful to decipher which strategies photosynthetic organisms use to cope with changeable environments.
Rodrigo Bedera‐García +3 more
wiley +1 more source
Synthetic Biology in Leishmaniasis: Design,simulation and validation of constructed Genetic circuit [PDF]
arXiv, 2013 Building circuits and studying their behavior in cells is a major goal of systems and synthetic biology. Synthetic biology enables the precise control of cellular states for systems studies, the discovery of novel parts, control strategies, and interactions for the design of robust synthetic systems. To the best of our knowledge,there are no literature
arxiv
Mesoscopic behavior from microscopic Markov dynamics and its application to calcium release channels [PDF]
, 2013 A major challenge in biology is to understand how molecular processes determine phenotypic features. We address this fundamental problem in a class of model systems by developing a general mathematical framework that allows the calculation of mesoscopic properties from the knowledge of microscopic Markovian transition probabilities.
arxiv +1 more source
Inositol phosphate pathway evolution and synthesis in Dictyostelium discoideum [PDF]
, 2020 Inositol phosphates (InsPs) are polar water-soluble derivatives of the six- carbon cyclitol inositol. They are synthesized, through phosphorylation reactions, by kinases of four distinct families: IPK, IP5-2K, ITPK1 and PPIP5K, which are thought to be ...
Portela Torres, Paloma
core
A tale of two inositol trisphosphates. [PDF]
, 2016 Between spring 1982 and autumn 1984 the physiological role of Ins(1,4,5)P3 as a calcium-mobilizing second messenger was first suggested and then experimentally established.
core +2 more sources