Results 141 to 150 of about 2,351 (231)
Inositol phosphate pathway evolution and synthesis in Dictyostelium discoideum [PDF]
Inositol phosphates (InsPs) are polar water-soluble derivatives of the six- carbon cyclitol inositol. They are synthesized, through phosphorylation reactions, by kinases of four distinct families: IPK, IP5-2K, ITPK1 and PPIP5K, which are thought to be ...
Portela Torres, Paloma
core
Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes
David Furkert +2 more
openalex +1 more source
Developing Dictyostelium discoideum as a model to study the synthesis and metabolism of inositol pyrophosphates and inorganic polyphosphate [PDF]
Inositol pyrophosphates and inorganic polyphosphate (polyP) represent two of the most phosphate-rich molecules in the cell. However, the synthesis, metabolism and function of these “high-energy” molecules are not well understood.
Livermore, TM
core
A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis
Inositol pyrophosphates (PP-InsPs) are eukaryotic nutrient messengers. The N-terminal kinase domain of diphosphoinositol pentakisphosphate kinase (PPIP5K) generates the messenger 1,5-InsP8, the C-terminal phosphatase domain catalyzes PP-InsP breakdown ...
Pierre Raia +8 more
doaj +1 more source
Inositol pyrophosphates (PP-InsPs) are nutrient messengers whose cellular levels are precisely regulated. Diphosphoinositol pentakisphosphate kinases (PPIP5Ks) generate the active signaling molecule 1,5-InsP8.
Florian Laurent +10 more
doaj +1 more source
How inositol pyrophosphates control cellular phosphate homeostasis?
Phosphorus in his phosphate PO(4)(3-) configuration is an essential constituent of all life forms. Phosphate diesters are at the core of nucleic acid structure, while phosphate monoester transmits information under the control of protein kinases and phosphatases.
openaire +3 more sources
Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. [PDF]
Rao F +13 more
europepmc +1 more source

